Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Living-DNA Nanogel Appendant Enables <i>In Situ</i> Modulation and Quantification of Regulation Effects on Membrane Proteins.

ACS applied bio materials·2022
Same author

Target-Dependent Gating of Nanopores Integrated with H-Cell: Toward A General Platform for Photoelectrochemical Bioanalysis.

Analytical chemistry·2021
Same author

Super-resolution plasmonic imaging via scattering saturation STED.

Chemical communications (Cambridge, England)·2021
Same author

Nucleolin-Targeted Ratiometric Fluorescent Carbon Dots with a Remarkably Large Emission Wavelength Shift for Precise Imaging of Cathepsin B in Living Cancer Cells.

Analytical chemistry·2021
Same author

Dark-Field Imaging of Cation Exchange Synthesis of Cu<sub>2-</sub>S@Au<sub>2</sub>S@Au Nanoplates toward the Plasmonic Enhanced Hydrogen Evolution Reaction.

ACS applied materials & interfaces·2021
Same author

Efficient NIR electrochemiluminescent dyes based on ruthenium(II) complexes containing an N-heterocyclic carbene ligand.

Chemical communications (Cambridge, England)·2021
Same journal

Microfluidic rare cell analysis beyond counting: workflow design from enrichment to multi-omics.

Lab on a chip·2026
Same journal

A sperm racetrack to separate sperm by swim speed.

Lab on a chip·2026
Same journal

Controlled encapsulation and droplet size prediction in two-step microfluidic double emulsions.

Lab on a chip·2026
Same journal

A particulate blood-mimicking fluid with physiological biconcave geometry for microscale hemorheology.

Lab on a chip·2026
Same journal

Multicellular sensor arrays fabricated by capillary stamping for pattern-based odor discrimination.

Lab on a chip·2026
Same journal

A real-time microfluidic surveillance system for multiplex detection of heavy metal contamination in wastewater.

Lab on a chip·2026
See all related articles

Related Experiment Video

Updated: Jun 8, 2026

Expanding Nanopatterned Substrates Using Stitch Technique for Nanotopographical Modulation of Cell Behavior
09:06

Expanding Nanopatterned Substrates Using Stitch Technique for Nanotopographical Modulation of Cell Behavior

Published on: December 8, 2016

Large scale lithography-free nano channel array on polystyrene.

Bi-Yi Xu1, Jing-Juan Xu, Xing-Hua Xia

  • 1Key Laboratory of Analytical Chemistry for Life Science, Ministry of Education of China, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, 210093, China.

Lab on a Chip
|October 6, 2010
PubMed
Summary
This summary is machine-generated.

Researchers developed a lithography-free nanochannel array using a simple cracking method on polystyrene. This technique creates controllable nanochannels for applications in nanofluidics, such as ion enrichment and current rectification devices.

More Related Videos

Large-area Scanning Probe Nanolithography Facilitated by Automated Alignment and Its Application to Substrate Fabrication for Cell Culture Studies
09:45

Large-area Scanning Probe Nanolithography Facilitated by Automated Alignment and Its Application to Substrate Fabrication for Cell Culture Studies

Published on: June 12, 2018

Fabrication of Nanoheight Channels Incorporating Surface Acoustic Wave Actuation via Lithium Niobate for Acoustic Nanofluidics
07:23

Fabrication of Nanoheight Channels Incorporating Surface Acoustic Wave Actuation via Lithium Niobate for Acoustic Nanofluidics

Published on: February 5, 2020

Related Experiment Videos

Last Updated: Jun 8, 2026

Expanding Nanopatterned Substrates Using Stitch Technique for Nanotopographical Modulation of Cell Behavior
09:06

Expanding Nanopatterned Substrates Using Stitch Technique for Nanotopographical Modulation of Cell Behavior

Published on: December 8, 2016

Large-area Scanning Probe Nanolithography Facilitated by Automated Alignment and Its Application to Substrate Fabrication for Cell Culture Studies
09:45

Large-area Scanning Probe Nanolithography Facilitated by Automated Alignment and Its Application to Substrate Fabrication for Cell Culture Studies

Published on: June 12, 2018

Fabrication of Nanoheight Channels Incorporating Surface Acoustic Wave Actuation via Lithium Niobate for Acoustic Nanofluidics
07:23

Fabrication of Nanoheight Channels Incorporating Surface Acoustic Wave Actuation via Lithium Niobate for Acoustic Nanofluidics

Published on: February 5, 2020

Area of Science:

  • Materials Science and Engineering
  • Nanotechnology
  • Physical Chemistry

Background:

  • Fabricating nanochannel arrays typically requires complex lithography techniques.
  • Developing cost-effective and scalable methods for nanochannel fabrication is crucial for advancing nanofluidics.

Purpose of the Study:

  • To report a novel, lithography-free method for fabricating nanochannel arrays.
  • To demonstrate the control over nanochannel dimensions and their replication for practical applications.

Main Methods:

  • Utilizing the cracking process on a polystyrene (PS) Petri dish surface.
  • Controlling uni-axial macromolecular chain alignment in polystyrene for parallel nanochannel formation.
  • Employing PDMS (polydimethylsiloxane) for replication of the PS nanochannel array.

Main Results:

  • Achieved parallel nanochannels with equal interspaces and controllable depths (20-200 nm).
  • Nanochannels with lengths up to tens of millimeters were successfully fabricated.
  • Demonstrated successful PDMS replication of the nanochannel array structure.

Conclusions:

  • The cracking method offers a simple and effective approach for lithography-free nanochannel array fabrication.
  • Replicated nanochannel arrays are applicable in nanofluidic devices, including ion enrichment and current rectification.
  • This method provides a scalable pathway for producing functional nanochannel structures for diverse applications.