[Innervation anomalies--mechanism of adaptation or embryonal malformation?]

After injuries innervationanomalies are observest. Are these anomalies mechanismen of adaption or an embryological malformation, is a still mansverst question. This paper tries some contributions to the answer. The use of modern muscleenzymhistochemistry in connection of histological findings of nerves in certain levels gives assertions on anomalies of innervation and mechanisms of reinnervation. After 14, 28, 56 and 112 days tissues of nerves and muscle from 66 female WISTAR-rats were investigated after various lesions. We have found in 15 not operated rats that the so called typegrouping can be a expression of reparation process after microlesions of nerve and muscle. We interpreted the anomalies as an expression of a reaction of adaption. The innervationanomalies succeeded in the fore and behind extremities of the rate indirectly. Above all embryological malformations can explain some anomalies of innervation on the fore extremities. We conclude from our results that communication among nerves and nerve bundles were developed or activated. These mechanism seems to be effective only about a short distance. We did not find a MARTIN-GRUBER-anostomosis. The findings of reinnervation of the musculature were attributed to cross-innervation, collateral and orthotope reinnervation. Generally the innervationanomalies are an expression of plasticity of the peripheral nervous system in all periods of life. In the first place we interpreted this phenomenous as adaption of nerves after injury and in the second place as embryological malformation.