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Carcinoma cheek: regional pattern and management.

Muhammad Ayub Musani¹, Itrat Jawed, Saleem Marfani

¹Department of ENT, Karachi Medical and Dental College, Abbasi Shaeed Hospital, Karachi. ayubmusani@yahoo.com

Journal of Ayub Medical College, Abbottabad : JAMC

|October 9, 2010

Summary

Carcinoma of the cheek is prevalent in Pakistan, affecting younger individuals. Early diagnosis and treatment of this oral cancer are crucial for better patient outcomes and survival rates.

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Area of Science:

Oncology
Head and Neck Surgery
Public Health

Background:

Oral cancer incidence varies globally, with higher rates in South-East Asia compared to Western countries.
In Pakistan, oral cancer is a significant health concern, ranking as the second most common cancer in both males and females.
This study focuses on carcinoma of the cheek, examining its regional patterns, causes, treatment, and prognosis.

Purpose of the Study:

To investigate the epidemiological patterns of cheek carcinoma in Karachi, Pakistan.
To identify etiological associations and risk factors contributing to cheek cancer.
To evaluate the management strategies and patient prognosis for carcinoma of the cheek.

Main Methods:

A prospective study of 45 primary cheek carcinoma cases was conducted between April 1995 and December 1998.

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Diagnostic tools included OPG and CT scans for tumor staging (TNM) and assessment of metastasis.

Treatment involved surgical excision, with 23 cases requiring reconstruction and 39 undergoing neck dissection, followed by adjuvant radiotherapy or chemoradiation.

Main Results:

The study included 45 patients (28 females, 17 males), with the most common age group being 41-50 years.
Squamous cell carcinoma (SCC) accounted for 95.5% of cases, with 68% presenting at the advanced T4 stage.
After a 3-year follow-up, 30 patients remained disease-free, indicating potential for successful treatment.

Conclusions:

Carcinoma of the cheek is a common malignancy in the region, increasingly observed in younger populations.
Promoting oral hygiene awareness and discouraging the use of social carcinogens are vital for preventing oral cancer.
Early detection and prompt treatment significantly improve the chances of cure, while advanced stages carry a poor prognosis.