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Hyperreactio luteinalis with preeclampsia.

Alev Atis1, Filiz Cifci, Yavuz Aydin

  • 1Obstetrician and Gynecologist, Sisli Etfal Training and Research Hospital, Istanbul, Turkey.

Journal of Emergencies, Trauma, and Shock
|October 9, 2010
PubMed
Summary
This summary is machine-generated.

Hyperreactio luteinalis (HL) causes enlarged ovaries due to benign theca lutein cysts, often found incidentally during cesarean sections. This condition can mimic malignancy, necessitating careful pathological examination to prevent unnecessary ovarian removal.

Keywords:
Hyperreactio luteinalispreeclampsiapregnancy

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Area of Science:

  • Reproductive Endocrinology
  • Gynecologic Pathology
  • Maternal-Fetal Medicine

Background:

  • Hyperreactio luteinalis (HL) is characterized by bilateral ovarian enlargement caused by theca lutein cysts.
  • It is a benign condition, frequently discovered incidentally during cesarean sections.
  • HL can present with an anaplastic appearance, potentially leading to misdiagnosis and unnecessary surgical intervention.

Observation:

  • A 24-year-old pregnant woman presented with bilateral ovarian enlargement at 35 weeks gestation.
  • She had preeclampsia and preterm contractions, necessitating a cesarean delivery due to breech presentation and nulliparity.
  • Intraoperative biopsy revealed multiple benign theca lutein cysts consistent with HL.

Findings:

  • This case represents the fourth reported instance of HL associated with preeclampsia in a normal singleton pregnancy.
  • Approximately 60% of HL cases occur independently of trophoblastic disease.
  • The anaplastic appearance of the ovaries in HL can mimic ovarian neoplasms.

Implications:

  • HL, particularly when associated with preeclampsia, may offer insights into the pathophysiology of this hypertensive disorder.
  • Accurate diagnosis of HL is crucial to avoid unnecessary ovarian resection.
  • Wedge biopsy and frozen section analysis are vital for differentiating HL from ovarian malignancies.