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Urinary tract infections in children with primary nephrotic syndrome and acute glomerulonephritis

O T Adedoyin1, I A Ojuawo, M S Odimayo

  • 1Department of Paediatrics, University of Ilorin Teaching Hospital, P.M.B.1459, Ilorin, Nigeria. ooadedoyin@yahoo.com

West African Journal of Medicine
|October 9, 2010
PubMed

Insights

Urinary tract infection (UTI) is uncommon in children newly diagnosed with acute glomerulonephritis (AGN) or nephrotic syndrome (NS). This study found a low prevalence of UTI in both pediatric kidney conditions.

Area of Science:

  • Pediatric Nephrology
  • Infectious Diseases in Children

Background:

  • Urinary tract infection (UTI) is frequently reported in children with nephrotic syndrome (NS).
  • Limited data exists on UTI occurrence in children with acute glomerulonephritis (AGN).
  • A comparative analysis of UTI susceptibility between AGN and NS in children is lacking.

Purpose of the Study:

  • To determine and compare the prevalence of urinary tract infection (UTI) in children with newly diagnosed acute glomerulonephritis (AGN) or nephrotic syndrome (NS).

Main Methods:

  • Retrospective review of urinary microscopy, culture, and sensitivity tests for children diagnosed with NS and AGN between 1996-2004.
  • Exclusion of children with NS who experienced relapse or received steroids, cytotoxic agents, or antibiotics prior to admission.

Main Results:

  • Three out of 35 children (9%) with AGN and one out of 32 children (3%) with NS were diagnosed with UTI.
  • Commonly isolated organisms in AGN patients included Coliforms, Klebsiella, and Staphylococcus aureus.
  • Coliform was the sole organism identified in the single NS patient with UTI.

Conclusions:

  • The prevalence of urinary tract infection (UTI) is low in children with newly diagnosed acute glomerulonephritis (AGN) and nephrotic syndrome (NS).
Abstract

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