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Published on: July 17, 2020
A new phenylpropanoid glycoside from Cirsium setosum
Rui Ke1, En-Yuan Zhu, Gui-xin Chou
1Key Laboratory of Standardization of Chinese Medicines of Ministry of Education, Institute of Chinese Materia Medica of Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Yao Xue Xue Bao = Acta Pharmaceutica Sinica
|October 12, 2010
Summary
Researchers isolated a new phenylpropanoid glycoside and three known compounds from Cirsium setosum (Willd.) MB. This study advances our understanding of the plant
Area of Science:
- Phytochemistry
- Natural Product Chemistry
- Pharmacognosy
Background:
- Cirsium setosum (Willd.) MB. is a plant with potential medicinal properties.
- Understanding its chemical constituents is crucial for exploring its therapeutic applications.
Purpose of the Study:
- To isolate and identify chemical constituents from the aerial parts of Cirsium setosum.
- To characterize a novel phenylpropanoid glycoside and known compounds.
Main Methods:
- Extraction of aerial parts using 70% ethanol.
- Isolation of compounds via column chromatography.
- Structure elucidation using spectral and chemical evidence.
Main Results:
- One new phenylpropanoid glycoside, sinapyl alcohol 9-O-(E)-p-coumaroyl-4-O-beta-D-glucopyanoside, was identified.
- Three known compounds: lycoperodine-1, apigenin-7-O-(6"-(E)-p-coumaroyl)-beta-D-galactopyranoside, and quercetin were isolated.
- Lycoperodine-1 was reported from the Cirsium genus for the first time.
- Apigenin-7-O-(6"-(E)-p-coumaroyl)-beta-D-galactopyranoside and quercetin were reported from this plant for the first time.
Conclusions:
- The chemical investigation of Cirsium setosum yielded a new phenylpropanoid glycoside and several known compounds.
- This study expands the phytochemical knowledge of the Cirsium genus and Cirsium setosum specifically.
- The identified compounds may contribute to the pharmacological profile of Cirsium setosum.
