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Updated: Jun 8, 2026

Quantitative Assessment Protocol for Facial Soft Tissue Volumetric Changes with Stereophotogrammetry
Published on: December 9, 2025
Age-related changes of the soft tissue profile from the second to the fourth decades of life
Lino Torlakovic1, Espen Faerøvig
1Department of Orthodontics, University of Oslo, Norway. linot@odont.uio.no
Objective:
To describe the age-related changes of the soft tissue facial profile from the second to fourth decades of life.
Materials And Methods:
Cephalograms from the same subjects in their 20s, 30s, and 40s were analyzed. A coordinate system analysis based on stable landmarks is used. A line connecting Walker's point (W) and sphenoethmoidal (SE) created the x-axis. Walker's point was origin. Depending on data distribution, landmark displacements from T1 to T2, from T2 to T3, and from T1 to T3 were analyzed using the paired t-test or the Wilcoxon test for zero expected change versus a two-sided alternative. For each landmark the mean, standard deviation, P value, and lower and higher 95% confidence intervals were calculated.
Results:
During T2-T1, for males, the whole profile was displaced anteriorly and slightly superiorly, and for females, the lower facial profile was displaced in a posterior and inferior direction. Greater changes occurred in the female profile than the male profile. During T3-T2, the female profile changed slightly while the male profile underwent great changes: the upper facial profile was displaced anteriorly, and the lower profile was displaced posteriorly. The whole profile was displaced in the inferior direction.
Conclusions:
Significant changes occurred in the soft tissue facial profile from the second to fourth decades. Aging of the male facial profile began 10 years later than for females; however, when the changes did occur, they were of greater magnitude. The upper facial profile was displaced in the anterior direction and the whole profile was displaced inferiorly for both sexes.
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