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Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

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Phase Contrast Magnetic Resonance Imaging in the Rat Common Carotid Artery
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Split-acquisition real-time CINE phase-contrast MR flow measurements.

Jennifer A Steeden1, David Atkinson, Andrew M Taylor

  • 1Centre for Medical Image Computing, UCL Department of Medical Physics and Bioengineering, London, United Kingdom.

Magnetic Resonance in Medicine
|October 13, 2010
PubMed
Summary

A new split-acquisition real-time phase-contrast MRI (PCMR) technique doubles frame rates, enhancing temporal or spatial resolution for improved cardiac flow imaging. This method offers accurate measurements in adults and children.

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Area of Science:

  • Medical Imaging
  • Cardiovascular Imaging
  • Magnetic Resonance Imaging

Background:

  • Real-time phase-contrast magnetic resonance (PCMR) imaging is limited by low temporal and spatial resolution due to interleaved acquisition of phase images.
  • Improving resolution is crucial for accurate assessment of cardiac function and blood flow dynamics.

Purpose of the Study:

  • To introduce and evaluate a novel split-acquisition real-time CINE PCMR technique.
  • To assess the impact of this technique on temporal and spatial resolution, and flow measurement accuracy.

Main Methods:

  • A split-acquisition technique was developed, dividing flow-encoded and flow-compensated data acquisition into separate blocks.
  • Magnitude images were used for automatic data matching in cardio-respiratory space to correct background phase offsets.
  • Two sequences were tested: one prioritizing high temporal resolution and another prioritizing high spatial resolution.

Main Results:

  • Both split-acquisition sequences demonstrated excellent agreement in stroke volume measurements in 20 adults compared to standard methods.
  • In pediatric studies, the high-spatial resolution sequence yielded more accurate flow measurements than interleaved real-time PCMR when compared to cardiac-gated PCMR.
  • The data matching technique proved accurate, with acceptable quantitative image quality metrics (SNR, VNR, edge sharpness).

Conclusions:

  • The split-acquisition real-time CINE PCMR technique effectively doubles the frame rate, enabling enhanced temporal or spatial resolution.
  • This improved resolution leads to more accurate flow quantification, particularly in pediatric populations.
  • The technique presents a valuable advancement for real-time cardiac MRI, offering improved diagnostic capabilities.