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Updated: Jul 28, 2026

Isolation, Fixation, and Immunofluorescence Imaging of Mouse Adrenal Glands
Published on: October 2, 2018
[Relationship between the hypophyseal-adrenal and the genital systems in silver-black foxes]
Abstract:
Interaction between the hypophysial-adrenal system (HAS) and the hypophysis-gonad system was studied. For this purpose the foxes were subjected to total gonadectomy 8 months before they were sacrificed. Functional activity of the HAS was judged by the hypophysis ACTH content, corticosteroid production by the adrenal cortex in vitro, and by the glucocorticoid concentration in the peripheral blood. Castration of male foxes foxes failed to influence the activity of various HAS links. Gonadectomy of females was accompanied by changes in the activity of individual HAS links in different direction--some reduction of ACTH in the hypophysis, a sharp and significant fall of the peripheral blood glucocorticoid level and a marked significant elevation of hydrococortisone production in the adrenal cortex in vitro.
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