Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Sleep Apnea01:21

Sleep Apnea

Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
Other Pulmonary Disorders01:17

Other Pulmonary Disorders

Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
Alterations in Respiration II01:30

Alterations in Respiration II

There are numerous types of normal and abnormal respiration. Based on ventilatory movements, breathing patterns are classified as regular, deep, or shallow. Examples include Biot's breathing, Cheyne-Stokes respiration, Kussmaul's breathing, hyperventilation, and hypoventilation. Each pattern is clinically significant and aids in evaluating patients.
In Biot's breathing, the respiratory rate and depth are irregular, alternating between periods of deep gasping and apnea. Common causes include...
Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
Sleep-Wake Cycles01:24

Sleep-Wake Cycles

Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and  rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
Physiological Control of Respiration01:23

Physiological Control of Respiration

Introduction
Breathing, a seemingly passive process, is regulated by the respiratory center in the brainstem. This center coordinates the involuntary control of respirations, which means it occurs without conscious effort, ensuring a smooth and uninterrupted pattern.
Regulation of Ventilation
The body maintains ventilation by monitoring levels of carbon dioxide (CO2), oxygen (O2), and hydrogen ion concentration (pH) in the arterial blood. Among these factors, the level of CO2 plays a crucial...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

2024 Position Statement on the Use of Different Diagnostic Methods for Sleep Disorders in Adults - Brazilian Sleep Association.

Sleep science (Sao Paulo, Brazil)·2024
Same author

2024 Standardization of Polysomnography Reports - A Consensus of the Brazilian Sleep Association.

Sleep science (Sao Paulo, Brazil)·2024
Same author

Brazilian Thoracic Association Consensus on Sleep-disordered Breathing.

Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia·2022
Same author

Long term oral appliance therapy decreases stress symptoms in patients with upper airway resistance syndrome.

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine·2020
Same author

Treatment of obstructive sleep apnea syndrome associated with stroke.

Sleep medicine·2015
Same author

[Diagnostic criteria and treatment for sleep-disordered breathing: RERA].

Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia·2010

Related Experiment Video

Updated: Jun 8, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

[Pathophysiology of sleep-disordered breathing].

Luciana de Oliveira Palombini1

  • 1Instituto do Sono de São Paulo, São Paulo, SP, Brasil. lpalombini@hotmail.com

Jornal Brasileiro De Pneumologia : Publicacao Oficial Da Sociedade Brasileira De Pneumologia E Tisilogia
|October 15, 2010
PubMed
Summary

During sleep, the respiratory system changes, increasing risks for breathing abnormalities. Factors like airway anatomy and genetics contribute to sleep-disordered breathing.

Area of Science:

  • Respiratory Physiology
  • Sleep Medicine
  • Genetics

Context:

  • Sleep involves significant respiratory system alterations, increasing vulnerability to abnormalities.
  • Transitioning to sleep elevates upper airway resistance and impairs protective reflexes.
  • Individuals with risk factors, like anatomical abnormalities, are more susceptible to sleep-disordered breathing.

Purpose:

  • To explore the multifactorial causes of sleep-disordered breathing.
  • To examine the role of anatomical and functional upper airway changes during sleep.
  • To understand the genetic and environmental contributions to sleep-disordered breathing.

Summary:

  • Sleep-disordered breathing is linked to reduced upper airway size, stemming from anatomical issues, neuromuscular alterations, and impaired airway receptors.

More Related Videos

Acupoint Application Combined with Ear Plaster Therapy for Treating Sleep Disorders with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
04:53

Acupoint Application Combined with Ear Plaster Therapy for Treating Sleep Disorders with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Published on: October 18, 2024

Related Experiment Videos

Last Updated: Jun 8, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

Acupoint Application Combined with Ear Plaster Therapy for Treating Sleep Disorders with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
04:53

Acupoint Application Combined with Ear Plaster Therapy for Treating Sleep Disorders with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Published on: October 18, 2024

  • Genetic predispositions and environmental factors such as allergies can increase the likelihood of developing sleep-disordered breathing.
  • Compensatory mechanisms for maintaining airway patency during wakefulness are less effective during sleep, especially in at-risk individuals.

    • Impact:

    • Highlights the complex interplay of factors contributing to sleep-disordered breathing.
    • Underscores the importance of considering anatomical, genetic, and environmental influences in sleep-related respiratory disorders.
    • Provides a foundation for further research into the pathophysiology and potential interventions for sleep-disordered breathing.