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Updated: Jun 8, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
[Obstructive sleep apnea in children]
Simone Chaves Fagondes1, Gustavo Antonio Moreira
1Serviço de Pneumologia, Laboratório do Sono, Hospital de Clinicas de Porto Alegre, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil. sfagondes@terra.com.br
Insights
Childhood obstructive sleep apnea syndrome (OSAS) affects 1-4% of children, presenting with snoring and breathing pauses during sleep. Diagnosis via polysomnography guides treatment, with surgery or CPAP being common options.
Area of Science:
- Pediatric Pulmonology
- Sleep Medicine
- Otolaryngology
Context:
- Childhood obstructive sleep apnea syndrome (OSAS) is a spectrum of upper airway obstruction during sleep, ranging from primary snoring to severe hypoventilation.
- Prevalence varies (1.5-15% for snoring, 1-4% for OSAS), with higher incidence in boys, overweight children, those of African ancestry, with atopy, or prematurity.
Purpose:
- To define childhood obstructive sleep apnea syndrome (OSAS), detailing its prevalence, risk factors, symptoms, diagnostic methods, and consequences.
- To outline the diagnostic gold standard (polysomnography) and current treatment modalities, including adenotonsillectomy and positive airway pressure (CPAP/Bilevel).
Summary:
- OSAS involves recurrent upper airway obstruction during sleep, leading to symptoms like loud snoring and apnea.
- Diagnosis relies on polysomnography, assessing cardiovascular, neurocognitive, and behavioral impacts.
- Treatment primarily involves adenotonsillectomy, with positive airway pressure therapies gaining traction.
Impact:
- Highlights the significant health impacts of pediatric OSAS, including cardiovascular, neurocognitive, and behavioral issues.
- Emphasizes the importance of timely diagnosis and appropriate treatment for improving outcomes in affected children.
Abstract:
Childhood obstructive sleep apnea syndrome (OSAS) is characterized by recurrent episodes of partial or complete upper airway obstruction during sleep. The disease encompasses a continuum from primary snoring (a benign condition without physiological alterations or associated complications) to increased upper airway resistance, obstructive hypoventilation and OSAS. The prevalence of snoring is high, ranging from 1.5% to 15%, depending on how it is defined. Based on parent-reported questionnaires and complementary tests, the prevalence of OSAS is 1-4%. This syndrome is more common in boys, overweight children, of African ancestry, with a history of atopy and prematurity. The most common symptoms are snoring that is frequent and loud; family-reported apnea; and restless sleep. The physical examination should assess growth status, signs of chronic upper airway obstruction, and craniofacial malformations. Overnight polysomnography is the gold standard test for the diagnosis and for the determination of the appropriate positive pressure level, as well as for postsurgical treatment evaluation. Intermittent hypoxia and multiple arousals resulting from obstructive events contribute to the well-described cardiovascular, neurocognitive, and behavioral consequences in pediatric patients with OSAS. Although the main treatment for OSAS in children is adenotonsillectomy, treatment with CPAP or Bilevel is becoming more widely used in the pediatric population.
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