Related Experiment Video
Updated: Jun 8, 2026

Improved Home Blood Pressure Control by CT-guided Ozone-mediated Renal Denervation for Patients with Resistant Hypertension
Published on: June 6, 2025
Improving blood pressure control: results of home-based post-acute care interventions
Liliana E Pezzin1, Penny H Feldman, Jennifer M Mongoven
1Department of Medicine and Center for Patient Care and Outcomes Research (PCOR), Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA. lpezzin@mcw.edu
Background:
Blood pressure (BP) control remains elusive for many Americans. Although home health nurses are uniquely positioned to help vulnerable individuals achieve BP control, hypertension (HTN) management has not been a high priority in post-acute care.
Objective:
To examine the effects of two home-based interventions designed to improve BP outcomes among high-risk African-American patients.
Design:
Cluster randomized controlled trial.
Participants:
A total of 845 newly admitted patients with uncontrolled HTN (JNC7 stages 1 or 2).
Interventions:
The "basic" intervention delivered key HTN information to clinicians and patients, and a home BP monitor to patients, while the patients received usual post-acute care. The "augmented" intervention provided more intensive and extensive HTN information, monitoring and feedback for 3 months beyond the index home care admission.
Measures:
Primary: BP control. Secondary: reductions in mmHG SBP and DBP, improvements in proportions improving JNC7 stage or achieving clinically meaningful reductions in SBP and DBP.
Methods:
Multivariate regression models.
Key Results:
The basic intervention produced no significant BP improvements; the augmented intervention significantly improved stage 2 patients' outcomes. Among stage 2 patients, the augmented intervention increased BP control by 8.7 percentage points relative to usual care (8.9% vs. 17.6%; p=0.01), yielded an 8.3 mmHG relative reduction in SBP (p=0.01), and increased the proportion achieving at least a 20 mmHG reduction in SBP by 16.4 percentage points (p=0.01).
Conclusion:
Among stage 2 patients, a nurse-led intervention providing additional HTN medication review and patient self-management support during the 3-month post-acute care period yielded significant improvements in 3-month BP control, plus improvements in secondary BP outcomes.
Related Concept Videos
Hypertension V: Nursing Management
Errors occurring during blood pressure monitoring
Several factors...
Hypertension IV: Drug Therapy and Lifestyle Modifications
Acute Coronary Syndrome IV: Interprofessional Care
Peripheral Artery Disease III: Interprofessional Care
Pre-Procedural Guidelines for Assessing Blood Pressure