Related Experiment Video
Updated: Jun 8, 2026

12:33
Origami Inspired Self-assembly of Patterned and Reconfigurable Particles
Published on: February 4, 2013
Remembrances of self-assemblies past.
1Department of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, Georgia 30322, United States.
Langmuir : the ACS Journal of Surfaces and Colloids
|October 16, 2010
Summary
This study explores self-assembly methods like micelles and vesicles using advanced techniques. It highlights how diverse investigative approaches illuminate complex self-assembled systems.
Area of Science:
- Physical Chemistry
- Materials Science
- Supramolecular Chemistry
Background:
- Self-assembly is crucial for creating complex structures.
- Understanding self-assembly mechanisms requires diverse analytical tools.
Purpose of the Study:
- To review and discuss various investigative methodologies for studying self-assemblies.
- To emphasize how different techniques uniquely contribute to understanding complex systems.
Main Methods:
- Kinetics, Nuclear Magnetic Resonance (NMR) spectroscopy (dynamic NMR, Pulsed Field Gradient NMR - PGSE-NMR), isotopic labeling (double-(13)C), computational modeling (molecular dynamics).
- Thermodynamic analysis (phase diagrams), advanced microscopy (cryo-high-resolution scanning electron microscopy - cryo-HRSEM, light microscopy, electron microscopy, confocal microscopy).
- Physicochemical characterization (rheology, electrophoretic mobility, electroformation, calorimetry).
Main Results:
- Each method provides distinct insights into the behavior and structure of self-assemblies.
- The synergy of multiple techniques offers a comprehensive understanding of complex systems.
- Specific techniques are highlighted for their unique contributions to studying micelles, coacervates, gels, and vesicles.
Conclusions:
- A multi-technique approach is essential for fully characterizing self-assembled systems.
- The choice of methodology significantly impacts the understanding of self-assembly processes.
- This work provides a framework for selecting appropriate investigative tools for self-assembly research.
Related Concept Videos
Assembly of Signaling Complexes
Multiprotein signaling complexes are formed in a dynamic process involving protein-protein interactions at the cytoplasmic domain of transmembrane receptors or enzymatic and non-enzymatic proteins associated with the receptor. These complexes ensure the activation and propagation of intracellular signals that regulate cell functions.
Interaction domains in cell signaling
Interaction domains recognize exposed features of their binding partners containing post-translationally modified sequences,...
Interaction domains in cell signaling
Interaction domains recognize exposed features of their binding partners containing post-translationally modified sequences,...
Assembly of Complex Microtubule Structures
Complex microtubule structures are present in resting cells and in dividing cells. In resting cells, they are responsible for maintaining the cellular architecture, tracks for intracellular transport, positioning of organelles, assembly of cilia and flagella. They mediate the bipolar spindle assembly for chromosomal segregation and positioning of the cell division plate in dividing cells. The formation of microtubule complex structures depends on the cell type, cell stage, and cell function.
Assembly of Cytoskeletal Filaments
Cytoskeletal filaments are polymeric forms of smaller protein subunits. However, individual cytoskeletal filaments may easily disassemble or associate with other similar filaments to form rigid structures. Microfilaments, made of actin monomers, rely on actin-binding proteins to form bundles and create networks of individual actin filaments. Microtubules rely on microtubule-associated proteins (MAPs) to form sturdy cylindrical structures. However, the proteins involved in forming complex...
Self-Schemas
In general, a schema is a mental construct consisting of a cluster or collection of related concepts (Bartlett, 1932). There are many different types of schemata, and they all have one thing in common: schemata are a method of organizing information that allows the brain to work more efficiently. When a schema is activated, the brain makes immediate assumptions about the person or object being observed.
Autobiographical Memory
Autobiographical memory is a unique type of episodic memory that involves recollecting personal life experiences. It allows individuals to remember significant events from their past, creating a narrative of their lives. One interesting phenomenon related to autobiographical memory is the reminiscence bump. This effect refers to the tendency of adults to recall more events from their second and third decades of life — typically between ages 10 to 30 — than from other periods. This period is...
The Sense of Self: Reflected Self-Appraisal and Social Comparison
According to Charles Cooley, we base our image on what we think other people see (Cooley 1902). We imagine how we must appear to others, then react to this speculation. We don certain clothes, prepare our hair in a particular manner, wear makeup, use cologne, and the like—all with the notion that our presentation of ourselves is going to affect how others perceive us. We expect a certain reaction, and, if lucky, we get the one we desire and feel good about it. But more than that, Cooley...

