Attributional intervention for depression in two people with multiple sclerosis (MS): single case design

Area of Science:

• Psychiatry
• Neuroscience
• Psychology

Background:

• Depression is a prevalent comorbidity in multiple sclerosis (MS).
• The hopelessness theory of depression, focusing on attributional style, is relevant for MS patients.
• Cognitive Behaviour Therapy (CBT) can modify attributional style and alleviate depression in MS.

Observation:

• This study investigated the impact of altering attributional style on depression in two individuals with MS.
• A 5-session intervention targeting attributional style was administered.
• An ABA research design was employed, monitoring attributional style, depressive symptoms, life events, and MS-related stressors.

Findings:

• The intervention demonstrated effectiveness for one participant, leading to significant reductions in depressive symptoms and sustained positive changes in attributional style.
• Observed improvements in the primary participant persisted for six months, with some reduction in effect.
• The intervention was less effective for the second participant, who discontinued treatment early.

Implications:

• The findings provide support for the hopelessness theory of depression within the context of MS.
• This research highlights the potential of targeting attributional style as a key component of CBT interventions for depression in individuals with MS.
• Further research is warranted to optimize CBT interventions for this population.