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Comparative Lesions Analysis Through a Targeted Sequencing Approach

Comparative Lesions Analysis Through a Targeted Sequencing Approach

Published on: November 5, 2019

Acrokeratosis paraneoplastica.

N Asokan¹, G T Nair, V Suja

¹Department of Dermatology and Venereology, Trivandrum Medical College, Trivandrum-695011, India.

Indian Journal of Dermatology, Venereology and Leprology

|October 16, 2010

Summary

This summary is machine-generated.

This report details a 60-year-old man diagnosed with hypopharyngeal squamous cell carcinoma and Bazex syndrome. This case highlights the rare association between these two conditions.

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Area of Science:

Oncology
Dermatology

Background:

Squamous cell carcinoma (SCC) is a common cancer.
Acral keratoses, specifically Bazex syndrome, are rare paraneoplastic syndromes often associated with underlying malignancy.

Purpose of the Study:

To report a rare case of a 60-year-old male patient presenting with both hypopharyngeal squamous cell carcinoma and Bazex syndrome.
To emphasize the importance of recognizing Bazex syndrome as a potential indicator of underlying malignancy, such as hypopharyngeal SCC.

Main Methods:

Case report presentation.
Review of patient's clinical presentation, diagnostic findings, and treatment.

Main Results:

The patient, a 60-year-old male, was diagnosed with squamous cell carcinoma of the hypopharynx.
The patient also exhibited symptoms consistent with acrokeratosis paraneoplastica (Bazex syndrome).

Conclusions:

Bazex syndrome can be an early sign of internal malignancy, including squamous cell carcinoma of the head and neck.
Early recognition and diagnosis of Bazex syndrome are crucial for timely detection and management of associated cancers.