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Cutaneous Leishmaniasis in the Dorsal Skin of Hamsters: a Useful Model for the Screening of Antileishmanial Drugs
Published on: April 21, 2012
Cutaneous leishmaniasis in Jodhpur district
1Department of Skin, STD and Leprosy, Mathura Dass Mathur Hospital, Dr Sampurnanand Medical College, Jodhpur - 342003, India.
Indian Journal of Dermatology, Venereology and Leprology
|October 16, 2010
Summary
A new endemic zone for cutaneous leishmaniasis was identified in Jodhpur, Rajasthan. Intralesional berberine sulfate showed promise in treating oriental sore cases.
Area of Science:
- Tropical Medicine and Infectious Diseases
- Dermatology
- Medical Parasitology
Background:
- Cutaneous leishmaniasis presents diverse epidemiological patterns globally.
- A novel endemic region for this disease has emerged in the Jodhpur district of Rajasthan, India.
Purpose of the Study:
- To describe the clinical features of cutaneous leishmaniasis cases in a newly identified endemic zone.
- To evaluate the efficacy of intralesional berberine sulfate in treating oriental sore.
Main Methods:
- Clinical observation and documentation of 21 smear-positive cutaneous leishmaniasis patients.
- Treatment assessment of oriental sore using intralesional berberine sulfate.
Main Results:
- Detailed clinical characteristics of 21 oriental sore cases from Jodhpur district were recorded over one year.
- Intralesional berberine sulfate demonstrated potential therapeutic value for oriental sore.
Conclusions:
- The Jodhpur district represents a new focus for cutaneous leishmaniasis in Rajasthan.
- Intralesional berberine sulfate warrants further investigation as a treatment for cutaneous leishmaniasis.
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