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Related Concept Videos

Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Endoscopic Procedures II: Colonoscopy01:25

Endoscopic Procedures II: Colonoscopy

The colon, or large intestine, is the final segment of the digestive system. Its primary functions include absorbing water and vitamins produced by gut bacteria and transforming waste from liquid to solid to form stool. In adults, the large intestine is approximately 5 feet long and consists of four main sections:
Tumor Progression02:07

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy01:26

Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy

This lesson explores three gastrointestinal imaging techniques: radionuclide testing, colonic transit studies, and virtual colonoscopy.
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and solid...
Serum Laboratory Studies, Stool Test, Breath Test01:30

Serum Laboratory Studies, Stool Test, Breath Test

Gastrointestinal (GI) diagnostic studies are pivotal in confirming, ruling out, diagnosing, or staging various diseases, including cancers. Following diagnosis, allocating time for discussions with the patient and providing informational resources is crucial. Diagnostic assessments of the GI tract often occur in outpatient settings like endoscopy suites or GI labs. Preparation for these tests may include dietary restrictions, fasting, liquid bowel preparations, laxatives, enemas, and the...

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Related Experiment Video

Updated: Jun 8, 2026

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection
07:35

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection

Published on: June 8, 2020

Updates in colorectal cancer screening.

John M Inadomi1

  • 1San Francisco General Hospital Suite 3D, 1001 Potrero Avenue, San Francisco, CA 94110 USA.

F1000 Medicine Reports
|October 16, 2010
PubMed
Summary

Updated colorectal cancer screening guidelines address mortality but vary in detecting flat neoplasia. Future efforts focus on improving adherence and addressing screening disparities.

Area of Science:

  • Gastroenterology
  • Oncology
  • Public Health

Background:

  • Colorectal cancer (CRC) screening guidelines have been updated by national societies.
  • Current screening methods exhibit variable efficacy in detecting colorectal neoplasia, particularly non-polypoid lesions.
  • Established age thresholds for CRC screening initiation and cessation may result in the omission of detectable lesions.

Purpose of the Study:

  • To review recent advances in colorectal cancer screening.
  • To highlight challenges in neoplasia detection, adherence, and disparities.
  • To emphasize the need for improved screening strategies and patient/provider education.

Main Methods:

  • Review of current literature and updated national guidelines on colorectal cancer screening.

Related Experiment Videos

Last Updated: Jun 8, 2026

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection
07:35

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection

Published on: June 8, 2020

  • Analysis of the diagnostic capabilities of various screening modalities for different types of colorectal neoplasia.
  • Examination of data regarding screening initiation/discontinuation ages and disparities in access and utilization.

    • Main Results:

    • Screening tests differ significantly in their ability to detect neoplasia, especially prevalent non-polypoid colorectal lesions.
    • Current age recommendations for initiating and ending screening may lead to missed diagnoses.
    • Significant disparities exist in the availability and utilization of colorectal cancer screening tests.

    Conclusions:

    • Enhancing adherence to recommended screening strategies is crucial for reducing colorectal cancer mortality.
    • Interventions focused on patient and provider education are necessary to address screening disparities.
    • Further research and guideline refinement are needed to optimize colorectal cancer screening efficacy and equity.