Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Endoscopic Incisional Therapy for Benign Esophageal Strictures: A Systematic Review and Meta-Analysis.

Journal of clinical gastroenterology·2026
Same author

Normalizing Catastrophe: Learning From Responses to Cancer Diagnosis.

JCO oncology practice·2026
Same author

Association of proximal adenomas with high-grade dysplasia with increased cumulative incidence of postpolypectomy colon cancer: A Surveillance, Epidemiology, and End Results-Medicare analysis.

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract·2026
Same author

Incremental Value of Adherence to Repeat Stool Test in Reducing Long-term Incidence of Colorectal Cancer.

Journal of clinical gastroenterology·2026
Same author

Colorectal Cancer Screening Test Preferences by Sociodemographic Factors and Health Beliefs in Diverse Underserved Populations.

Digestive diseases and sciences·2026
Same author

Accuracy of endoscopic ultrasound for staging esophageal and gastroesophageal junction neoplasia prior to endoscopic submucosal dissection.

Scandinavian journal of gastroenterology·2026
Same journal

How important is fiber in the Crohn's disease story?

Gastroenterology·2026
Same journal

Reply to "Critical Appraisal of the Integrin αV-YAP-CTGF Axis in Congestive Hepatopathy".

Gastroenterology·2026
Same journal

Critical Appraisal of the Integrin αV-YAP-CTGF Axis in Congestive Hepatopathy.

Gastroenterology·2026
Same journal

A High-Risk Impaction: To Scope or to Stent First?

Gastroenterology·2026
Same journal

Epithelial FOXP3 orchestrates O-glycosylated IL-6 secretion to drive pancreatic fibrocarcinogenesis.

Gastroenterology·2026
Same journal

Reply to "Methodological Considerations on Neonatal Metabolomics and Future Inflammatory Bowel Disease".

Gastroenterology·2026
See all related articles

Related Experiment Video

Updated: Apr 5, 2026

E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy
06:28

E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy

Published on: August 1, 2019

9.4K

Interventions for Increasing Colorectal Cancer Screening Uptake: A Systematic Review and Network Meta-Analysis.

Daryl Ramai1, Chun-Wei Pan2, Bjorn Rodriguez3

  • 1Division of Gastroenterology, Hepatology, and Nutrition, University of Utah, Salt Lake City, Utah.

Gastroenterology
|April 3, 2026
PubMed
Summary
This summary is machine-generated.

Patient navigation and mailed fecal immunochemical test (FIT) outreach are most effective for increasing colorectal cancer screening. Educational multimedia shows promise in high-uptake settings and recent studies.

Keywords:
Colorectal CancerNavigationOutreachScreening Uptake

More Related Videos

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection
07:35

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection

Published on: June 8, 2020

7.5K
Structured Approach to Colonoscopy Technique Optimization: A Single-Center Experience with Novice Endoscopists
03:43

Structured Approach to Colonoscopy Technique Optimization: A Single-Center Experience with Novice Endoscopists

Published on: July 11, 2025

960

Related Experiment Videos

Last Updated: Apr 5, 2026

E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy
06:28

E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy

Published on: August 1, 2019

9.4K
Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection
07:35

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection

Published on: June 8, 2020

7.5K
Structured Approach to Colonoscopy Technique Optimization: A Single-Center Experience with Novice Endoscopists
03:43

Structured Approach to Colonoscopy Technique Optimization: A Single-Center Experience with Novice Endoscopists

Published on: July 11, 2025

960

Area of Science:

  • Oncology
  • Public Health
  • Preventive Medicine

Background:

  • Colorectal cancer screening significantly reduces mortality.
  • Screening uptake remains suboptimal despite its benefits.
  • Comparative effectiveness of various interventions to improve screening rates is unclear.

Purpose of the Study:

  • To evaluate the effectiveness of different colorectal cancer screening uptake interventions.
  • To compare strategies using a systematic review and network meta-analysis.

Main Methods:

  • Analysis of 76 randomized clinical trials across eight intervention strategies.
  • Network meta-analysis comparing interventions using risk ratios (RRs) and 95% confidence intervals (CIs).
  • Assessment of intervention rankings, risk of bias, and certainty of evidence (GRADE framework).

Main Results:

  • Patient navigation (RR 1.58) and mailed FIT outreach (RR 1.36) were most effective, significantly outperforming usual care.
  • Mailed FIT outreach was superior to colonoscopy outreach (RR 1.35); patient navigation outperformed reminder-only interventions (RR 1.48).
  • In low baseline uptake settings (<30%), mailed FIT outreach was most effective (RR 3.12); educational multimedia performed best in higher uptake populations (≥30%) and recent studies (2021-2024).

Conclusions:

  • Patient navigation and mailed FIT outreach are the most effective strategies for increasing colorectal cancer screening uptake.
  • These interventions are particularly impactful in populations with low baseline screening rates.
  • Educational multimedia offers a scalable alternative, showing promise in recent years and high-uptake settings.