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Related Concept Videos

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Multiple Sclerosis l: Introduction

Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...
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Updated: Jun 8, 2026

Murine Bilateral Renal Lymphadenectomy
06:31

Murine Bilateral Renal Lymphadenectomy

Published on: December 30, 2025

Multicentric lupus vulgaris.

S Ramachandra1, R K Chawla, R S Moorthy

  • 1Department of Dermatology & STD, Military Hospital, Pathankot - 145001, Punjab, India, .

Indian Journal of Dermatology, Venereology and Leprology
|October 19, 2010
PubMed
Summary
This summary is machine-generated.

A 60-year-old female experienced disseminated tuberculosis, a severe form of the disease affecting multiple organs. This case highlights the impact of poor health on tuberculosis progression and spread.

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Published on: November 1, 2015

Area of Science:

  • Medical Microbiology
  • Infectious Diseases
  • Dermatology

Background:

  • Tuberculosis (TB) is a significant global health challenge.
  • Disseminated tuberculosis involves widespread organ involvement.
  • Lupus vulgaris is a cutaneous manifestation of tuberculosis.

Purpose of the Study:

  • To report a rare case of disseminated tuberculosis with multicentric lupus vulgaris.
  • To illustrate the potential for extensive disease spread from cutaneous TB.
  • To emphasize the role of host health in TB dissemination.

Main Methods:

  • Case report of a 60-year-old female patient.
  • Clinical presentation and diagnostic findings.
  • Review of literature on disseminated TB and lupus vulgaris.

Main Results:

  • The patient presented with multicentric lupus vulgaris.
  • Disseminated tuberculosis affected joints, bones, lymph nodes, and lungs.
  • Haematogenous spread was attributed to the patient's compromised health status.

Conclusions:

  • Multicentric lupus vulgaris can be a precursor to disseminated tuberculosis.
  • Poor general health significantly increases the risk of TB dissemination.
  • Early recognition and management of cutaneous TB are crucial to prevent systemic spread.