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Spontaneous Murine Model of Anaplastic Thyroid Cancer

Spontaneous Murine Model of Anaplastic Thyroid Cancer

Published on: February 3, 2023

Metastasis in differentiated thyroid carcinoma.

M A Azim¹, K S Salam, M K Khan

¹Dr Md Abdul Azim, Junior Consultant, Department of ENT, Mymensingh Medical College Hospital (MMCH), Mymensingh, Bangladesh.

Mymensingh Medical Journal : MMJ

|October 20, 2010

Summary

Differentiated thyroid carcinoma (DTC) is more common in females. Papillary carcinoma, the most frequent type, shows higher lymph node metastasis rates, while follicular carcinoma presents more distant metastasis.

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Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

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Area of Science:

Oncology
Otorhinolaryngology

Background:

Differentiated thyroid carcinoma (DTC) is a common endocrine malignancy.
Understanding the epidemiological and clinical characteristics of DTC is crucial for patient management.

Purpose of the Study:

To analyze the epidemiological features and patterns of metastasis in differentiated thyroid carcinoma patients.
To compare the characteristics of papillary and follicular carcinoma subtypes.

Main Methods:

Retrospective analysis of 70 differentiated thyroid carcinoma patients.
Data collected from March 2003 to March 2005 at three medical college hospitals.
Evaluation of patient demographics, tumor types, and metastasis patterns.

Main Results:

Female patients were more commonly affected (2.6:1 ratio).
Papillary carcinoma (77.15%) was more prevalent than follicular carcinoma (22.85%).
Lymph node metastasis was higher in papillary (35%) versus follicular (12.5%) carcinoma; distant metastasis was higher in follicular (12.5%) versus papillary (3.70%).
Maximum lymph node metastasis occurred in level 3 (55%) and level 2 (45%).

Conclusions:

Papillary carcinoma is the predominant subtype of DTC with a higher propensity for lymph node metastasis.
Follicular carcinoma shows a greater tendency for distant metastasis.
Metastasis patterns differ significantly between papillary and follicular thyroid carcinoma subtypes, influencing clinical management strategies.