[Non-invasive investigation of human brain function]
1Department of System Neuroscience, School of Medicine, Sapporo Medical University.
Rinsho Shinkeigaku = Clinical Neurology
|October 22, 2010
Summary
Exploring brain function has evolved from invasive 19th-century methods to advanced, non-invasive techniques. New high-sensitivity measures allow detailed brain mapping in normal subjects, offering fresh insights.
Area of Science:
- Neuroscience
- Brain Mapping
- Cognitive Science
Context:
- Historical localization of brain function established in the 19th century.
- Intraoperative stimulation/suppression, while secure, is invasive with limitations.
- Advancements in high-sensitivity, non-invasive measures enable external brain function monitoring.
Purpose:
- To review the evolution of brain function exploration methods.
- To highlight the advantages of non-invasive techniques for studying brain function.
- To emphasize the potential of combining multiple methods for deeper brain insights.
Summary:
- Traditional brain function studies relied on invasive methods like intraoperative stimulation.
- Modern non-invasive techniques measure physical phenomena linked to brain activity from outside the skull.
- These advanced methods allow for repeated measurements in normal subjects, yielding novel findings.
Impact:
- Facilitates safer and more accessible research into brain function.
- Enables comprehensive brain mapping and understanding of neural processes.
- Promotes the integration of diverse techniques for enhanced neuroscientific discovery.


