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Acute and Chronic Models of Hyperglycemia in Zebrafish: A Method to Assess the Impact of Hyperglycemia on Neurogenesis and the Biodistribution of Radiolabeled Molecules
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The effects of hyperglycemia on adrenal cortex function and steroidogenesis in the zebrafish

Jamie W Powers1, Jaime K Mazilu, Shuo Lin

  • 1Division of Neonatology, Mattel Children's Hospital, University of California Los Angeles, Los Angeles, CA 90095, USA.

Molecular Genetics and Metabolism
|October 22, 2010
PubMed

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Adrenal hormones play a pivotal role in maintaining the body's electrolyte balance and orchestrating responses to stress, showcasing the intricate functions of the adrenal cortex and medulla.
The adrenal cortex, a powerhouse of hormone synthesis, generates over two dozen corticosteroid hormones. The zona glomerulosa produces mineralocorticoids, exemplified by aldosterone, influencing the electrolyte composition of body fluids. The synthesis of glucocorticoids such as cortisol and corticosterone...