Related Experiment Video
Updated: Jun 7, 2026

Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
Simple assessment of patient's stage of chronic kidney disease using eGFR-MDRD nomograms
Sunny Eloot1, Bruno Van Vlem, Johan De Meester
1Department of Nephrology, Dialysis Unit 1P8, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium. sunny.eloot@ugent.be
Abstract:
European as well as US guidelines recommend the Modification of Diet in Renal Disease (MDRD) formula to determine the glomerular filtration rate (GFR) and, based on this, the staging of chronic kidney disease (CKD). The diagnosis of CKD is only established when a reduced eGFR has been observed for 3 months or longer. Because the MDRD equation is very complex, the calculation of eGFR is not possible without help from calculators or computers. Therefore, we converted this equation into simple, easy to use colour nomograms. These were drawn separately for men and women, on one hand, and for whites and blacks, on the other. These nomograms allow the determination of a patient's eGFR in a quick and easy way and at any location.
Related Concept Videos
Drug Dosing in Renal Diseases: Estimation of Glomerular Filtration Rate Based on Serum Creatinine Concentration
Chronic Kidney Disease III: Interprofessional Care
Chronic Kidney Disease I: Introduction
Drug Dosing in Renal Diseases: Measurement of Glomerular Filtration Rate
Factors Affecting Renal Clearance: Renal Impairment
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
Drug Dosing in Renal Diseases: Measurement of Serum Creatinine Concentration and Clearance
