Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
Methods of Documentation V: CBE01:23

Methods of Documentation V: CBE

Charting by Exception, or CBE, is a method of documentation used in healthcare, particularly in nursing, that focuses on documenting only significant or abnormal findings rather than recording every detail. This approach aims to streamline the documentation process, improve efficiency, and ensure that healthcare providers can quickly identify deviations from normalcy in patient assessments.
In CBE, healthcare professionals establish predefined standards of practice that define what constitutes...
Regression Toward the Mean01:52

Regression Toward the Mean

Regression toward the mean (“RTM”) is a phenomenon in which extremely high or low values—for example, and individual’s blood pressure at a particular moment—appear closer to a group’s average upon remeasuring. Although this statistical peculiarity is the result of random error and chance, it has been problematic across various medical, scientific, financial and psychological applications. In particular, RTM, if not taken into account, can interfere when researchers try to extrapolate results...
Dosage Regimens: Partial Pharmacokinetic Parameters01:01

Dosage Regimens: Partial Pharmacokinetic Parameters

It is not uncommon for complete drug pharmacokinetic profiles to remain elusive in pharmacokinetics. This necessitates certain educated assumptions by pharmacokineticists to determine appropriate dosage regimens without comprehensive pharmacokinetic data from animal or human studies. One prevalent assumption is setting the bioavailability factor, denoted as F, to 1 or 100%. This assumption caters to the scenario where a drug doesn't achieve full systemic absorption, resulting in the patient...
Henderson-Hasselbalch Equation02:48

Henderson-Hasselbalch Equation

The ionization-constant expression for a solution of a weak acid can be written as:
Fundamental Mathematical Principles in Pharmacokinetics: Calculus and Graphs01:21

Fundamental Mathematical Principles in Pharmacokinetics: Calculus and Graphs

The fundamental mathematical principles, such as calculus and graphs, play crucial roles in analyzing drug movement and determining pharmacokinetic parameters. Differential calculus examines rates of change and helps to determine the dissolution rate of drugs in biofluids, as well as how drug concentrations change over time. For instance, it can help calculate the rate of elimination of a drug from the body based on its concentration-time profile.
On the other hand, integral calculus focuses on...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Functional analysis of Box II mutations in yeast site-specific recombinases Flp and R. Significance of amino acid conservation within the Int family and the yeast sub-family.

Journal of molecular biology·1992
Same author

Fluorescence study of the ligand stereospecificity for binding to lumazine protein.

European journal of biochemistry·1992
Same author

Reduction of postoperative adhesions in strabismus surgery.

Korean journal of ophthalmology : KJO·1992
Same author

The Red Cross and CDC's natural-disaster surveillance system.

American journal of public health·1992
Same author

Cumulative logit modelling for ordinal response variables: applications to biomedical research.

Computer applications in the biosciences : CABIOS·1992
Same author

The sagittal ramus osteotomy. Stability of fixation with internal miniplates.

International journal of oral and maxillofacial surgery·1992
Same journal

Interfacial Behavior and Adsorption Mechanisms of Sorbitol Polyether Ester Emulsifiers in D-Phase Emulsion Systems: Applications for Spontaneous Emulsification.

Langmuir : the ACS journal of surfaces and colloids·2026
Same journal

Ti<sub>3</sub> Cluster-Doped 2D Goldene Surface for Electronic and Optical Sensing of Oxygen, Nitrogen, and Hydrocarbon-Based Respiratory Biomarkers: A DFT Study.

Langmuir : the ACS journal of surfaces and colloids·2026
Same journal

Condensation of GO<i>x</i> by Restoring Global Protein Fold on Diazo-Enriched SG Surfaces: Reinstallation of FADs Restores Biocatalytic Sustainability in Quantifying Blood Glucose.

Langmuir : the ACS journal of surfaces and colloids·2026
Same journal

Correction to "Protein Encapsulated DNA Metal Nanocluster as Fluorescent Nanoprobe for Detecting Insulin".

Langmuir : the ACS journal of surfaces and colloids·2026
Same journal

Rational Design of V<sub>2</sub>O<sub>5</sub> Hierarchical Microspheres with Tunable Porosities and Primary Building Blocks for Enhanced Lithium Storage Performance.

Langmuir : the ACS journal of surfaces and colloids·2026
Same journal

Roles of Anion and Cation Doping in g-C<b><sub>3</sub></b>N<b><sub>4</sub></b> as Artificial SEI for Regulating Interfacial Zn<b><sup>2+</sup></b> Deposition in Aqueous Zinc Metal Anodes.

Langmuir : the ACS journal of surfaces and colloids·2026
See all related articles

Related Experiment Video

Updated: Jun 7, 2026

Colon Ascendens Stent Peritonitis (CASP) - a Standardized Model for Polymicrobial Abdominal Sepsis
06:45

Colon Ascendens Stent Peritonitis (CASP) - a Standardized Model for Polymicrobial Abdominal Sepsis

Published on: December 18, 2010

Is the Cassie-Baxter formula relevant?

Y Kwon1, S Choi, N Anantharaju

  • 1School of Mechanical and Aerospace Engineering, Seoul National University, Seoul, Korea.

Langmuir : the ACS Journal of Surfaces and Colloids
|October 23, 2010
PubMed
Summary
This summary is machine-generated.

The Cassie-Baxter formula generally predicts contact angles on rough hydrophobic surfaces, but deviations occur at the advancing front of pillar-type roughness due to microscopic contact line distortions.

Related Experiment Videos

Last Updated: Jun 7, 2026

Colon Ascendens Stent Peritonitis (CASP) - a Standardized Model for Polymicrobial Abdominal Sepsis
06:45

Colon Ascendens Stent Peritonitis (CASP) - a Standardized Model for Polymicrobial Abdominal Sepsis

Published on: December 18, 2010

Area of Science:

  • Surface Science and Materials Chemistry
  • Wettability and Fluid Dynamics

Background:

  • The Cassie-Baxter formula is widely used to predict the apparent contact angle on rough hydrophobic surfaces.
  • Recent studies have questioned the universal applicability of the Cassie-Baxter formula, particularly for complex roughness geometries.

Purpose of the Study:

  • To experimentally and numerically investigate the validity of the Cassie-Baxter formula for predicting contact angles on various rough hydrophobic surfaces.
  • To identify conditions and mechanisms leading to deviations from the Cassie-Baxter predictions.

Main Methods:

  • Experimental measurements of advancing and receding contact angles on pillar-type and other rough hydrophobic surfaces.
  • Numerical simulations to model droplet behavior and contact line dynamics.
  • Correlation analysis between contact angle deviations and microscopic contact line distortions.

Main Results:

  • Contact angles generally follow the Cassie-Baxter formula's trend across different surface roughness types.
  • Significant deviations from the Cassie-Baxter predictions were observed specifically at the advancing front on pillar-type roughness.
  • A direct one-to-one correlation was found between these deviations and microscopic distortions of the contact line from its idealized Cassie-Baxter state.

Conclusions:

  • The Cassie-Baxter formula remains a useful approximation for apparent contact angles on many rough hydrophobic surfaces.
  • Microscopic contact line behavior, especially on specific geometries like pillar roughness, is critical and can lead to deviations from theoretical predictions.
  • Understanding these microscopic distortions is key to accurately predicting droplet behavior on advanced hydrophobic materials.