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Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
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Hospital antibiogram: a necessity.

S Joshi1

  • 1Department of Microbiology, Manipal Hospital, 98 Rustom Bagh, HAL Airport Road, Bangalore, India. sangeetajo@yahoo.com

Indian Journal of Medical Microbiology
|October 23, 2010
PubMed
Summary
This summary is machine-generated.

Hospital antibiograms provide crucial data on local bacterial resistance patterns, aiding clinicians in selecting appropriate antibiotic therapies and monitoring trends. This summary is essential for developing effective antibiotic policies and improving patient care.

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Area of Science:

  • Clinical Microbiology
  • Infectious Diseases
  • Public Health

Background:

  • Hospital antibiograms are periodic summaries of local bacterial antimicrobial susceptibilities.
  • Clinicians use antibiograms to guide empiric antibiotic therapy and monitor resistance trends.
  • Accurate antibiograms are essential for developing institutional antibiotic policies.

Purpose of the Study:

  • To outline the utility and methodology of constructing hospital antibiograms.
  • To emphasize the importance of antibiograms in antimicrobial stewardship and institutional accreditation.
  • To highlight future directions for antibiogram development, including patient data integration.

Main Methods:

  • Data extraction from hospital clinical microbiology laboratory records.
  • Analysis using WHONET software, incorporating Clinical and Laboratory Standards Institute (CLSI) guidelines.
  • Inclusion of only the first isolate per patient, analyzed by location and specimen type.

Main Results:

  • Antibiograms present percentage susceptibility of common bacterial isolates, ideally in tabular format.
  • Standardized methods ensure reliable data for clinical decision-making.
  • Easy accessibility of antibiograms (print or intranet) is crucial for clinicians.

Conclusions:

  • Hospital antibiograms are fundamental tools for antimicrobial stewardship and infection control.
  • Standardized construction and accessibility enhance their clinical utility.
  • Future antibiograms incorporating patient data will improve outbreak prediction and treatment reliability.