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Updated: Jun 7, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Unusual documentation of the transformation of a nevus into malignant melanoma
It is well documented that congenital nevi have a statistical chance of becoming malignant; however, it is unusual to actually follow the progression of such an event. A 48-year-old man photographically documented changes in his own nevus, which was present at birth, over a period of six months. Seeing this evolution in one lesion is interesting. Emphasis must not only be placed upon the importance of early diagnosis, but also on the expeditious removal of suspicious nevi and treatment.
It is well documented that congenital nevi have a statistical chance of becoming malignant; however, it is unusual to actually follow the progression of such an event. A 48-year-old man photographically documented changes in his own nevus, which was present at birth, over a period of six months. Seeing this evolution in one lesion is interesting. Emphasis must not only be placed upon the importance of early diagnosis, but also on the expeditious removal of suspicious nevi and treatment.
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