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Updated: Jun 5, 2026

Minimally Invasive Isolated Limb Perfusion (MI-ILP) for Locally Advanced Melanomas and Sarcomas of the Extremity
Published on: January 31, 2025
Rare malignant neoplasm of the leg: diagnosis and management dilemma
Abstract:
This case report highlights a rare, virulent, aggressive, poorly differentiated, epithelioid fibrosarcoma with numerous rhabdoid cells on the tibial aspect of an 84-year-old woman. Biopsy of the lesions were reviewed at College of Physicians and Surgeons of Columbia University Department of Dermatopathology (New York, New York) and in consultation with the Soft Tissue Pathology Division of the Surgical Pathology Department at Columbia University as well as the Department of Pathology at the Massachusetts General Hospital Division of Bone and Soft Tissue Pathology. The management of this patient was difficult especially considering her mental status. She had an excellent response to radiation therapy. It is important to be innovative in treatment and to use judgment when assessing unusual entities.