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Updated: Jun 7, 2026

Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation
Published on: August 26, 2014
A new, safer, controllable field-of-view endoscope avoiding movement inside body cavities
Keri Kim1, Hiroki Kamiuchi, Ken Masamune
1Graduate School of Information Science and Technology, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan. jazzpian@gmail.com
Abstract:
One of the greatest difficulties in endoscopic surgery is the limited field-of-view (FOV) of endoscopes. During endoscopic manipulation in body cavities to expand the FOV, there is the risk of inadvertent damage to body tissues, nerves, and internal organs. The risk increases especially in surgery that is performed inside a very small cavity, or in which body tissues are very fragile. To overcome these issues, we developed a novel endoscope that can provide various FOVs without moving or bending the endoscope itself inside the body cavity and investigated the feasibility of using the new endoscope in vivo. A beam splitter was used to visualize both forward and side views, and two polarization plates and observation windows were used to avoid overlap of the two views. An endoscope having a 7-mm diameter was fabricated through which both views were clearly visualized in vivo. It took only 0.7s to change the FOV with high repeatability, with a maximum distance error of 2.8%. The new endoscope can provide forward and panoramic views without moving the endoscope; therefore, the risk of inadvertent damage to fragile body tissues can be significantly decreased.
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