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The survey of Helicobacter pylori infection in infant

Mandana Rafeey1, Mahnaz Sadeghi Shabestari, Ali Rafiey

  • 1Liver and Gastrointestinal Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Pakistan Journal of Biological Sciences : PJBS
|October 27, 2010
PubMed

Insights

This study found a low prevalence of Helicobacter pylori (H. pylori) infection in infants in Northwest Iran. No correlation was observed between H. pylori infection rates and infant age.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Gastroenterology

Background:

  • * Helicobacter pylori (H. pylori) infection is a significant global health concern, particularly in pediatric populations.
  • * Understanding the prevalence and risk factors in infants is crucial for early diagnosis and management.
  • * Previous research indicates varied prevalence rates across different geographical regions and age groups.

Purpose of the Study:

  • * To determine the prevalence of H. pylori infection in infants aged two years or younger in Northwest Iran.
  • * To investigate the correlation between H. pylori infection and infant age.
  • * To explore potential associations between H. pylori infection and maternal education level and infant feeding practices.

Main Methods:

  • * A prospective descriptive study was conducted at Tabriz Children Hospital.
  • * Participants included infants up to two years old diagnosed with H. pylori infection via endoscopy and biopsy.
  • * Data on infant age, maternal education, and feeding history were collected and analyzed.

Main Results:

  • * The overall prevalence of H. pylori infection in the studied infant population was low.
  • * A statistically significant higher prevalence was observed in infants of mothers with lower education levels (p = 0.045).
  • * No significant correlation was found between H. pylori infection rates and the age of the infants (p = 0.5).
  • * H. pylori prevalence did not differ significantly between exclusively breastfed infants and those never breastfed (26.6% vs. 13.3%, p = 0.2).

Conclusions:

  • * H. pylori infection prevalence in infants in Northwest Iran is low.
  • * Maternal education level may be a relevant factor associated with H. pylori infection in infants.
  • * Infant age is not a significant predictor of H. pylori infection rates in this population.

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