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Updated: Jun 7, 2026

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

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Published on: September 20, 2018

Infantile scurvy: two case reports.

Leila Ghedira Besbes¹, Samir Haddad, Chebil Ben Meriem

¹Pediatric Department, Fattouma Bourguiba Hospital, Monastir 5000, Tunisia.

International Journal of Pediatrics

|October 27, 2010

Summary

Scurvy, a vitamin C deficiency disease, is rare in children but can occur in those with developmental delays. Subperiosteal hematomas are key indicators for diagnosing pediatric scurvy.

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Area of Science:

Pediatrics
Nutrition
Hematology

Background:

Ascorbic acid (vitamin C) is vital for collagen synthesis, antioxidant activity, and iron absorption.
Scurvy, resulting from vitamin C deficiency, is rare but persists in nutritionally at-risk populations.
Pediatric scurvy incidence is notably low.

Observation:

This report details two pediatric cases of scurvy.
Both children presented with cerebral palsy and developmental delay.
Subperiosteal hematomas were the presenting sign in both cases.

Findings:

Scurvy is exceptionally uncommon in the pediatric demographic.
Musculoskeletal symptoms, particularly subperiosteal hematomas, are significant in pediatric scurvy.
Multiple subperiosteal hematomas serve as a crucial diagnostic marker.

Implications:

Highlights the importance of considering scurvy in children with developmental disorders and unexplained hematomas.
Emphasizes the diagnostic value of musculoskeletal manifestations in pediatric scurvy.
Underscores the need for nutritional assessment in high-risk pediatric populations.