Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 7, 2026

Trabecular Bone Microarchitecture Evaluation in an Osteoporosis Mouse Model
06:59

Trabecular Bone Microarchitecture Evaluation in an Osteoporosis Mouse Model

Published on: September 8, 2023

Methodological considerations for analyzing trabecular architecture: an example from the primate hand.

Tracy L Kivell1, Matthew M Skinner, Richard Lazenby

  • 1Department of Human Evolution, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany. tracy_kivell@eva.mpg.de

Journal of Anatomy
|October 28, 2010
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Genetic diversity of late Neanderthals in northwestern Europe.

Nature·2026
Same author

Identification of functionally related adaptations in the trabecular network of the proximal femur and tibia of a bipedally trained Japanese macaque.

Anthropological science : journal of the Anthropological Society of Nippon = Jinruigaku zasshi·2026
Same author

Swartkrans <i>Paranthropus</i> and Sterkfontein <i>Australopithecus</i> from southern Africa had different locomotor repertoires.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

First multi-individual Neanderthal mitogenomes from north of the Carpathians.

Current biology : CB·2026
Same author

Frequency of arboreality is correlated with longer hand skeletons in Gorilla: Analysis of a new skeletal sample of Bwindi mountain gorillas.

Journal of anatomy·2026
Same author

Correction: Curated character of the Initial Upper Palaeolithic lithic artefact assemblages in Bacho Kiro Cave (Bulgaria).

PloS one·2026

Methodological choices in micro-computed tomography, specifically volume of interest (VOI) size and location, significantly impact trabecular bone analysis in primate hands. Careful consideration is crucial for accurate functional interpretations.

Area of Science:

  • Primate paleontology
  • Biomechanics
  • Comparative anatomy

Background:

  • Micro-computed tomography (micro-CT) is used to analyze trabecular bone architecture and its relation to primate behavior.
  • Methodological choices, such as volume of interest (VOI) selection, can influence trabecular bone characterization, especially in small, complex bones.
  • Previous studies noted susceptibility of some trabecular parameters to methodological variations.

Purpose of the Study:

  • To investigate the impact of VOI size and location on trabecular parameters in primate hand bones.
  • To quantify these effects in the capitate and third metacarpal of diverse nonhuman primates.

Main Methods:

  • Micro-CT analysis of trabecular bone architecture in the capitate and third metacarpal of various nonhuman primates.

More Related Videos

Dissection, MicroCT Scanning and Morphometric Analyses of the Baculum
04:32

Dissection, MicroCT Scanning and Morphometric Analyses of the Baculum

Published on: March 19, 2017

Outer-Boundary Assisted Segmentation and Quantification of Trabecular Bones by an Imagej Plugin
09:36

Outer-Boundary Assisted Segmentation and Quantification of Trabecular Bones by an Imagej Plugin

Published on: March 14, 2018

Related Experiment Videos

Last Updated: Jun 7, 2026

Trabecular Bone Microarchitecture Evaluation in an Osteoporosis Mouse Model
06:59

Trabecular Bone Microarchitecture Evaluation in an Osteoporosis Mouse Model

Published on: September 8, 2023

Dissection, MicroCT Scanning and Morphometric Analyses of the Baculum
04:32

Dissection, MicroCT Scanning and Morphometric Analyses of the Baculum

Published on: March 19, 2017

Outer-Boundary Assisted Segmentation and Quantification of Trabecular Bones by an Imagej Plugin
09:36

Outer-Boundary Assisted Segmentation and Quantification of Trabecular Bones by an Imagej Plugin

Published on: March 14, 2018

  • Systematic variation of VOI size and location within these hand bones.
  • Quantification of standard trabecular parameters, including connectivity, structure, anisotropy, and orientation.

    • Main Results:

    • VOI location significantly affected most trabecular parameters, particularly connectivity, structure (rods vs. plates), anisotropy, and trabecular orientation.
    • VOI size also influenced trabecular parameters, though to a lesser extent than location.
    • These effects were pronounced in the small, irregularly shaped hand bones studied.

    Conclusions:

    • VOI selection is a critical methodological factor in micro-CT analysis of primate hand bone trabecular architecture.
    • Understanding and accounting for VOI-induced biases are essential for robust comparative analyses and functional interpretations.
    • This study quantifies the impact of VOI choices, aiding future research on primate skeletal anatomy and positional behavior.