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Leveraging Turbidity and Thromboelastography for Complementary Clot Characterization
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Published on: June 4, 2020

Thromboelastography in veterinary medicine.

Bo Wiinberg1, Annemarie T Kristensen

  • 1The Small Animal Hospital, Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Frederiksberg, Denmark. bwi@life.ku.dk

Seminars in Thrombosis and Hemostasis
|October 28, 2010
PubMed
Summary
This summary is machine-generated.

Thromboelastography (TEG) aids in diagnosing animal coagulopathies like cancer and critical illness. This versatile tool monitors drug effects, showing promise in veterinary medicine for comprehensive coagulation assessment.

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Area of Science:

  • Veterinary Medicine
  • Hemostasis and Thrombosis
  • Animal Research

Background:

  • Thromboelastography (TEG) has a long history in animal research since the 1960s.
  • Clinical application of TEG in animals has become routine in the last decade.
  • TEG's capabilities and limitations in animals mirror those seen in human studies.

Purpose of the Study:

  • To review the current applications and established utility of TEG in veterinary medicine.
  • To highlight TEG's role in diagnosing and monitoring coagulopathies in animals.
  • To discuss the use of TEG in evaluating anticoagulant and procoagulant therapies in animal models.

Main Methods:

  • Review of existing literature on Thromboelastography (TEG) in animal studies and clinical practice.
  • Analysis of data regarding TEG's diagnostic and monitoring capabilities for various animal conditions.
  • Comparison of TEG performance with conventional coagulation assays in animal models.

Main Results:

  • TEG effectively diagnoses hypercoagulability in animals with disseminated intravascular coagulation, cancer, and critical illness.
  • The technique is well-established for detecting and monitoring diverse coagulopathies in both clinical and experimental animal settings.
  • TEG demonstrates superior performance over conventional assays in monitoring the effects of pro- and anticoagulant drugs in animals.

Conclusions:

  • TEG is a valuable and established tool in veterinary medicine for assessing hemostasis.
  • The scope and limitations of TEG in animals are comparable to those in humans.
  • The increasing use of TEG promises a wealth of new data on animal coagulation in the near future.