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Related Experiment Video

Updated: Jun 7, 2026

Online Repetitive Transcranial Magnetic Stimulation of Dorsomedial and Dorsolateral Prefrontal Cortex in Cognition Decision Making, and Cognitive Dissonance
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Online Repetitive Transcranial Magnetic Stimulation of Dorsomedial and Dorsolateral Prefrontal Cortex in Cognition Decision Making, and Cognitive Dissonance

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Decision threshold modulation in the human brain.

Philippe Domenech1, Jean-Claude Dreher

  • 1Cognitive Neuroscience Center, Reward and Decision-Making Group, Centre National pour la Recherche Scientifique, Unité Mixte de Recherche 5229, 69675 Bron, France. pdomenech@isc.cnrs.fr

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
|October 29, 2010
PubMed
Summary
This summary is machine-generated.

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Predicting upcoming events optimizes decision-making by lowering the decision threshold. The anterior cingulate cortex (ACC) and dorsolateral prefrontal cortex (DLPFC) work together, with ACC regulating threshold distance and DLPFC processing sensory evidence.

Area of Science:

  • Cognitive Neuroscience
  • Decision Science
  • Computational Neuroscience

Background:

  • Perceptual decisions rely on accumulating sensory evidence to reach a threshold.
  • Contextual predictability influences decision-making, but underlying mechanisms are unclear.
  • Models propose threshold distance adjustment or sensory evidence gain control.

Purpose of the Study:

  • Investigate how event predictability regulates perceptual decision-making.
  • Elucidate the neural mechanisms of contextual regulation in decision processes.
  • Characterize the roles of the anterior cingulate cortex (ACC) and dorsolateral prefrontal cortex (DLPFC).

Main Methods:

  • Model-driven functional magnetic resonance imaging (fMRI).
  • Information theory framework.

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Last Updated: Jun 7, 2026

Online Repetitive Transcranial Magnetic Stimulation of Dorsomedial and Dorsolateral Prefrontal Cortex in Cognition Decision Making, and Cognitive Dissonance
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Published on: December 5, 2025

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  • Analysis of decision threshold and sensory evidence accumulation.

    • Main Results:

    • Event predictability reduces the distance to the decision threshold.
    • ACC adjusts threshold distance based on predictive information.
    • DLPFC codes sensory evidence accumulation.
    • ACC-DLPFC information flow increases with computational complexity.

    Conclusions:

    • Predictability optimizes decisions by adjusting the decision threshold distance.
    • ACC and DLPFC exhibit distinct roles in context-dependent decision-making.
    • Neural communication between ACC and DLPFC supports complex regulatory computations.