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Published on: July 31, 2017
Managing irritability and aggression in autism spectrum disorders in children and adolescents
1Department of Psychiatry and Pediatrics, George Washington University Medical Center, Children's National Medical Center, Washington, DC, USA. arobb@cnmc.org
Abstract:
Children with autism and autism spectrum disorders have a high rate of irritability and aggressive symptoms. In one study up to 20% of children with autism have symptoms of irritability and aggression including aggression, severe tantrums, and deliberate self injurious behavior (Lecavalier [2006] J. Autism Dev. Disord. 36:1101-1114.). These symptoms can lead to impairment and distress in both home and school settings. Medications to treat the irritability will be discussed across categories of antipsychotics, antidepressants, antihypertensive agents, and others. Emphasis will be placed on medications with the most safety and efficacy and FDA approval.
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