Surgical therapy of malignant gliomas

The authors have presented the current state of surgical therapy of malignant gliomas underlining the advantages and disadvantages of traditional and stereotactic surgery, preparation for surgery, mortality, morbidity, prognostic factors, and complications. Particular attention was placed on cell kinetic studies. Of the methods used in this study we would like to recall those of flow cytometry associated with administration of BUdR and utilization of the monoclonal antibody Ki-67 associated with immunohistochemical techniques.