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Antiparkinsonian activity and dopamine receptor binding studies of imidazolone derivatives
P K Naithani1, V K Srivastava, A K Saxena
1Department of Pharmacology and Therapeutics, King George's Medical College, Lucknow, India.
Indian Journal of Experimental Biology
|December 1, 1990
Abstract:
Mannich bases and styryl derivatives of imidazolones were evaluated for their antiparkinsonian activity. Two compounds showed potent antiparkinsonian activity. These active compounds also showed binding with dopamine receptors in striatal membrane preparation of rat brain.