[Cerebral hemorrhage associated with the use phenylpropanolamine]

Phenylpropanolamine is a sympatheticomimetic agent which is widely used in pharmacologic preparations to treat nasal congestion, and to produce and anorexigenic or stimulant action. In the last years complications affecting the nervous system or the general condition have been reported. There is still controversy with regard to the safety of this pharmacologic agent. In this study we report two cases of parenchymal cerebral hemorrhage secondary to phenylpropanolamine administration. In the second case we observed angiographic findings of a reversible vasculopathy.