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Mechanistic study and kinetic determination of vitamin C
1Chemistry Department, College of Sciences, King Fahd University of Petroleum and Minerals, Dhahran, Saudi Arabia.
Journal of Pharmaceutical and Biomedical Analysis
|January 1, 1990
Abstract:
A simple specific method for the determination of vitamin C has been investigated by elucidating the reaction mechanism of its oxidation with cerium(IV) in sulphuric acid media. The reaction kinetics and rate measurements which form the basis of this method were determined by following the decrease of the intense yellow colour of cerium(IV) at 405 nm. The fixed-time and fixed-concentration methods were investigated. The former was found to be more precise and was consequently used for the determination. Advantages of this method over the B.P. and other methods are discussed.