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Kinetic determination of sotalol by oxidation with sodium vanadate
S M Sultan1, A M Bukhari, H Perzanowski
1Department of Chemistry, King Fahd University of Petroleum and Minerals, Dhahran, Saudi Arabia.
Journal of Pharmaceutical and Biomedical Analysis
|January 1, 1990
Abstract:
A kinetic method is described for the determination of sotalol. The method uses 0.033 M sodium vanadate to oxidize sotalol in 4 M sulphuric acid. The solution is heated at 90 degrees C and the absorbance is measured at 750 nm at a fixed time of 30 min. The concentration (c) of sotalol is calculated from the absorbance (A) by the equation: A = 0.04 + 0.0015625 c.