Related Experiment Video
Updated: Jul 26, 2026

06:34
A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
Published on: June 4, 2017
Allergic and nonallergic rhinitis: their characterization in a tropical environment
D Perdomo de Ponce1, M Uribe, I Wolff
1Hospital de Clínicas Caracas, Venezuela.
Investigacion Clinica
|January 1, 1990
Summary
This study found allergic rhinitis is common in tropical Venezuela, with symptoms like conjunctivitis, sinusitis, and asthma. Findings suggest similar patterns to industrialized nations.
Area of Science:
- Immunology
- Allergology
- Otorhinolaryngology
Background:
- Rhinitis, a common condition, presents in allergic and non-allergic forms.
- Understanding the prevalence and characteristics of allergic rhinitis in diverse geographic regions is crucial.
Purpose of the Study:
- To evaluate the differences between allergic and non-allergic rhinitis in a tropical urban population in Venezuela.
- To identify associated conditions and symptom patterns in patients with allergic rhinitis.
Main Methods:
- A cohort of 127 individuals was studied.
- Data collection included medical history, physical examination, nasal cytology, immunodiagnostic tests, routine laboratory tests, and sinus X-rays.
- Patients were classified into allergic rhinitis (AR), probable AR, infectious rhinitis, mixed rhinitis, non-allergic non-eosinophilic rhinitis, and control groups.
Main Results:
- Allergic rhinitis was diagnosed in 49 patients.
- Associated findings in allergic rhinitis patients included conjunctivitis (62%), sinusitis (23%), and bronchial asthma (24%).
- Infectious rhinitis was observed in 13 patients, with 50 individuals serving as controls.
Conclusions:
- Allergic rhinitis demonstrates a significant prevalence in this Venezuelan tropical urban population.
- The symptom patterns observed in allergic rhinitis patients are comparable to those reported in industrialized countries.
- Further research into rhinitis in tropical regions is warranted.
Related Concept Videos
Allergic Reactions
Overview
Allergic Drug Reactions
Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing numerous...
Drugs Used in Upper Respiratory Disorders: Overview
Upper respiratory tract disorders, including viral infections and allergic rhinitis, cause significant discomfort and disrupt daily life. Managing these conditions involves a variety of drugs, such as antihistamines, intranasal steroids, decongestants, antitussives, expectorants, and mucolytics. Specific examples of drugs in each category are provided.
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
Asthma: Pathogenesis and Management
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Allergic Reactions: Anaphylaxis
Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...
Asthma I: Introduction
Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...

