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Oxidation of nucleosides and nucleotides by peroxosulfate ions
T Itahara1, S Koga, T Yoshitake
1Institute of Chemistry, College of Liberal Arts, Kagoshima University, Japan.
Nucleic Acids Symposium Series
|January 1, 1990
Abstract:
Treatment of 5-methylpyrimidine nucleosides and nucleotides with sodium peroxodisulfate in sodium phosphate buffer solution at pH 7.0 at 75 degrees C resulted in the selective oxidation of the methyl group. On the other hand, oxidation of thymidine by potassium peroxomonosulfate gave thymidine glycols.