Related Experiment Video
Updated: Jun 7, 2026
11:50
A Standardized Pipeline for Examining Human Cerebellar Grey Matter Morphometry using Structural Magnetic Resonance Imaging
Published on: February 4, 2022
Central core of the cerebrum
Chan-Young Choi1, Seong-Rok Han, Gi-Taek Yee
1Department of Neurological Surgery, Ilsan Paik Hospital, College of Medicine, Inje University, Goyang, South Korea. cychoi@medigate.net
Journal of Neurosurgery
|October 30, 2010
Summary
This study used fiber dissection to map the 3D anatomy of the central core, revealing complex white matter and gray matter relationships. Understanding these spatial connections is crucial for neurosurgical approaches.
Area of Science:
- Neuroanatomy
- Neurosurgery
- Microscopic Dissection
Background:
- The central core of the brain contains complex white matter fibers and subcortical gray matter structures.
- Understanding the precise 3D relationships within this region is vital for surgical planning.
Purpose of the Study:
- To elucidate the intricate 3D spatial relationships of white matter tracts and subcortical gray matter within the central core.
- To provide anatomical insights beneficial for neurosurgical procedures.
Main Methods:
- Microscopic fiber dissection technique applied to four cerebral hemispheres (lateral and medial aspects).
Main Results:
- Detailed the components of the central core, including the extreme, external, and internal capsules, basal ganglia, amygdala, diencephalon, and various white matter tracts.
- Described the cerebral isthmus, connecting the central core to the hemisphere, and its composition of white matter fibers.
- Identified the inclusion of rostral corpus callosum fibers within the frontal cerebral isthmus.
Conclusions:
- Fiber dissection provides a valuable method for understanding the complex anatomy of the central core.
- This detailed anatomical knowledge aids neurosurgeons in planning and executing safe and effective surgical approaches.
Related Concept Videos
01:11Cerebrum: Anatomical Overview II
Each cerebral hemisphere can be divided into three main regions. The outermost region, the cerebral cortex, is a thin layer (2 to 4 millimeters thick) made up of gray matter, consisting of neuron cell bodies, dendrites, glial cells, and blood vessels. The middle region, or white matter, is primarily composed of myelinated nerve fibers organized into three types of large tracts: association fibers, commissures, and projection fibers. Association fibers connect different areas within the same...
01:17Cerebellum: Anatomical Regions
The cerebellum, also known as the "little brain," is located in the posterior cranial fossa, inferior to the tentorium cerebelli and dorsal to the brainstem. It plays a significant role in motor control, coordination, and proprioception.
Cerebellar Structure
Externally, the cerebellum features a highly convoluted surface with numerous folia (narrow ridges) separated by shallow sulci (grooves). The cerebellum is divided into two hemispheres by a thin median structure known as the vermis. The...
Cerebellar Structure
Externally, the cerebellum features a highly convoluted surface with numerous folia (narrow ridges) separated by shallow sulci (grooves). The cerebellum is divided into two hemispheres by a thin median structure known as the vermis. The...
01:26Cerebrum: Anatomical Overview I
The main and largest component of the human brain is the cerebrum. The cerebrum consists of two main parts: the cerebral cortex, an outer layer with wrinkles or folds known as gyri and shallow grooves called sulci, and a deeper region beneath it. The cerebrum divides into two distinct hemispheres and contains five different lobes: the frontal, parietal, temporal, occipital, and insula. The central sulcus separates the frontal and parietal lobes and two functionally important gyri — the...
01:20Anatomy of the Brain: Major Regions
The brain is the most complex organ in the human body. It consists of four main parts: the cerebrum, diencephalon, cerebellum, and brainstem.
The cerebrum is the largest section of the brain and divides into left and right hemispheres, separated by a deep fissure. The cerebral outer layer of grey matter — the cerebral cortex — comprises elevations called gyri and shallow groves called sulci. The inner portion of white matter includes long nerve fibers known as axons, which connect various areas...
The cerebrum is the largest section of the brain and divides into left and right hemispheres, separated by a deep fissure. The cerebral outer layer of grey matter — the cerebral cortex — comprises elevations called gyri and shallow groves called sulci. The inner portion of white matter includes long nerve fibers known as axons, which connect various areas...
01:30Organization of the Brain
The brain is an integral component of the nervous system and serves as the center for processing sensory inputs, making decisions, and directing bodily actions. This complex organ is organized into three primary sections: the hindbrain, midbrain, and forebrain, each responsible for a range of vital functions.
Hindbrain
The hindbrain, located at the base of the brain, plays a vital role in regulating automatic processes that sustain life. It includes the medulla oblongata, which is essential for...
Hindbrain
The hindbrain, located at the base of the brain, plays a vital role in regulating automatic processes that sustain life. It includes the medulla oblongata, which is essential for...
01:05Cerebral Hemispheres
The human brain, a complex organ, is functionally divided into two cerebral hemispheres—left and right. These hemispheres are interconnected by a structure of paramount importance, the corpus callosum. This substantial bundle of neural fibers is not just a bridge between the hemispheres but a crucial element for the brain's comprehensive functioning. It enables efficient communication between the two hemispheres, allowing each side of the brain to control and receive sensory and motor...