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Updated: Jun 7, 2026

Transesophageal Atrial Burst Pacing for Atrial Fibrillation Induction in Rats
Published on: February 14, 2022
ATRX: Put me on repeat
Iestyn Whitehouse1, Tom Owen-Hughes
1Sloan-Kettering Institute, New York, NY 10065, USA.
Abstract:
Mutations in the chromatin-remodeling protein ATRX cause alpha thalassaemia and mental retardation, but the severity of the disorder is independent of the specific mutation. In this issue of Cell, Law et al. (2010) demonstrate that ATRX alters gene expression by binding to G-rich tandem repeats, and the degree of transcriptional silencing caused by ATRX mutations correlates with the number of repeats.
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