Exposure to combustion of solid fuel and tuberculosis: a matched case-control study
M Gninafon1, G Ade, N Aït-Khaled
1Centre National Hospitalier de Pneumophysiologie, Cotonou, Benin.
The European Respiratory Journal
|October 30, 2010
Summary
Exposure to solid fuel combustion, such as coal and biomass, showed a weak and not statistically significant association with tuberculosis in Benin. Further research is needed to understand risk factors for tuberculosis.
Area of Science:
- Environmental Health
- Infectious Diseases Epidemiology
- Public Health
Background:
- Tuberculosis (TB) remains a significant global health challenge, particularly in low-resource settings.
- Exposure to indoor air pollution from solid fuel combustion is a suspected risk factor for respiratory diseases, including TB.
Purpose of the Study:
- To investigate the association between exposure to combustion of solid fuel (coal and biomass) and tuberculosis in Benin.
- To identify risk factors associated with tuberculosis in the study population.
Main Methods:
- A case-control study was conducted in Benin.
- 200 new sputum smear-positive tuberculosis cases and 400 neighborhood controls were enrolled.
- Univariate and multivariate conditional logistic regression analyses were performed.
Main Results:
- In univariate analysis, using solid fuel for cooking, ever smoking, male sex, daily alcohol use, and a family history of TB were significantly associated with TB.
- However, after adjusting for other factors in a multivariate model, the association between solid fuel use and TB was not statistically significant (adjusted OR 1.4, 95% CI 0.7-2.7).
Conclusions:
- The study found a weak and non-significant association between exposure to solid fuel combustion and tuberculosis in Benin.
- Other factors like smoking and family history appear to be stronger predictors of tuberculosis in this population.
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