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Related Concept Videos

Probiotics01:22

Probiotics

Probiotics are live, non-pathogenic microorganisms that confer health benefits by modulating the gut microbiota. The human gastrointestinal tract harbors a complex microbial ecosystem, and the balance of this microbiota is crucial for digestive and systemic health. Among the most extensively studied and utilized probiotics are species formerly classified within the genera Lactobacillus and Bifidobacterium. These organisms not only naturally colonize the human gut but are also consumed through...
Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
Bioavailability Enhancement: Drug Stability Enhancement and GI Retention01:05

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Improving a drug's stability in the gastrointestinal (GI) tract is paramount for enhancing its bioavailability and therapeutic effectiveness. Various strategies are employed to protect the drug from the harsh gastric milieu and to ensure its release and absorption at the desired site within the GI tract.Polymer coatings are one such method used to shield drugs from the stomach's acidic environment. By preventing premature drug release, these coatings improve the bioavailability of unstable...
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Microbes in the Production of Fermented Foods

Lactic acid bacteria (LAB) and molds are instrumental in fermenting plant-based foods to enhance preservation and ensure year-round availability. These microbial processes convert plant carbohydrates into organic acids and other metabolites that inhibit spoilage organisms and contribute to the sensory qualities of the final product.In sauerkraut production, cabbage goes through a microbial succession that starts with cocci such as Leuconostoc mesenteroides. These microbes begin fermentation by...
Microbes in Food Production01:29

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Microbial fermentation is central to food biotechnology, enhancing flavor, texture, preservation, and stability. Fermentative microorganisms metabolize carbohydrates into organic acids, alcohols, and other metabolites that inhibit spoilage organisms and improve digestibility while contributing distinctive sensory qualities.In baking, amylases naturally present in flour hydrolyze starch into monosaccharides such as glucose, which Saccharomyces cerevisiae ferments anaerobically. Through...
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Process Development for the Spray-Drying of Probiotic Bacteria and Evaluation of the Product Quality
05:45

Process Development for the Spray-Drying of Probiotic Bacteria and Evaluation of the Product Quality

Published on: April 7, 2023

Microencapsulation of live probiotic bacteria.

Mohammad Ariful Islam1, Cheol-Heui Yun, Yun-Jaie Choi

  • 1Department of Agricultural Biotechnology, Seoul National University, Seoul 151-921, South Korea.

Journal of Microbiology and Biotechnology
|October 30, 2010
PubMed
Summary
This summary is machine-generated.

Microencapsulation enhances probiotic survival and stability, crucial for their therapeutic benefits. This review explores alginate systems with chitosan and polylysine coatings for improved delivery of live bacterial cells.

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Published on: August 30, 2016

Area of Science:

  • Microbiology
  • Biotechnology
  • Food Science

Background:

  • Live bacterial cells, known as probiotics, offer health benefits but face survival challenges.
  • Poor stability in food products and the gastrointestinal tract limits probiotic efficacy.
  • Microencapsulation is a promising strategy to enhance probiotic viability and delivery.

Purpose of the Study:

  • To review the significance of microencapsulating live probiotic bacteria.
  • To explore the use of alginate microparticulate systems for probiotic encapsulation.
  • To evaluate coating polymers like chitosan and polylysine for enhanced stability.

Main Methods:

  • Review of scientific literature on probiotic microencapsulation.
  • Focus on alginate-based microparticulate systems.
  • Analysis of coating materials (chitosan, polylysine) for stability improvement.

Main Results:

  • Alginate microencapsulation improves probiotic survival and stability.
  • Coating polymers like chitosan and polylysine further enhance the protective effect.
  • Microencapsulation addresses challenges of probiotic delivery in food and the GI tract.

Conclusions:

  • Microencapsulation is vital for maximizing probiotic therapeutic potential.
  • Alginate systems, enhanced by chitosan or polylysine, offer a robust solution.
  • Further research into optimized coating strategies is warranted for effective probiotic applications.