Related Experiment Video
Updated: Jun 7, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
Dynamic among periodontal disease, stress, and adverse pregnancy outcomes
John J Arteaga-Guerra1, Virginia Cerón-Souza, Ana C Mafla
1Dentistry School, Universidad Cooperativa de Colombia, Pasto, Colombia. john.arteaga@correoucc.edu.co
Objective:
The aim of this study was to determine the dynamic between periodontitis and stress and the incidence of preterm birth (PTB), low birth weight (LBW) and preterm low birth weight (PLBW) in pregnant women from Pasto, Nariño, Colombia.
Methods:
Forty-six women who attended to "Hospital Local Civil" localized in the city were involved. Periodontal clinical evaluation, pregnancy outcome variables and a stress scale were collected. Data were analyzed using descriptive and analytic statistics.
Results:
The incidence of PTB was 13 %, of LBW was 4.3 %, and the occurrence of PLBW was 21.7 %. Our findings showed that the presence of periodontitis and stress all together increase the risk of LBW babies (OR=4.6; 95 % CI: 0.2-86.6). Regarding, periodontitis and stress interaction, the risk of PTB (OR=0.9; 95 % CI: 0.08-9.6) and PLBW (OR=1.1; 95 % CI: 0.1-7.1) decreased in the presence of these two variables, although their values were higher in the absent of stress (PTB, OR=2.3; 95 % CI: 0.3- 14.7 and PLBW, OR=10.3; 95 % CI:1.1-93.2).
Conclusions:
The periodontal disease in this study was associated with PTB, LBW and PLBW. However, their risk depends on the physiological changes produced by stress.
Related Concept Videos
Development of the Oral Microbiota
The Oral Microbiota
Psychoneuroimmunology: Cardiovascular Disease
A key area of focus in PNI is the relationship between stress and coronary...
Stress Prevention and Stress Management Techniques IV
Introduction to Stress and Lifestyle
Stress and Mental Health
Individuals with depression often experience challenges in both their personal and professional...