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Updated: Jun 7, 2026

Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs
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Published on: October 31, 2025

Neonatal fluid management.

Isabelle Murat1, Alexis Humblot, Laure Girault

  • 1Department of Anesthesia, Hôpital d'Enfants Armand Trousseau, 26 avenue du Dr. Arnold Netter, 75571 Paris, Cedex 12, France. isabelle.murat@trs.aphp.fr

Best Practice & Research. Clinical Anaesthesiology
|November 2, 2010
PubMed
Summary
This summary is machine-generated.

Neonatal fluid management during surgery requires careful consideration of unique physiological needs. This review focuses on essential fluid maintenance and replacement strategies for surgical neonates.

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Area of Science:

  • Anesthesiology
  • Neonatalogy
  • Pediatric Surgery

Background:

  • Perioperative fluid management in pediatrics is controversial, yet neonatal fluid management is often overlooked in guidelines.
  • Limited recent data exists on neonatal fluid management, primarily in pediatric textbooks, excluding resuscitation and shock management.
  • Neonates undergoing surgery often present with organ malformations or dysfunction, complicating fluid balance.

Purpose of the Study:

  • To review fundamental physiological principles relevant to neonatal fluid management.
  • To focus on fluid maintenance and replacement strategies specifically for neonates during surgical procedures.

Main Methods:

  • Literature review of physiological considerations in neonatal fluid management.
  • Focus on fluid maintenance and replacement during anesthesia and surgery.

Main Results:

  • Identified gaps in current guidelines regarding neonatal perioperative fluid management.
  • Highlighted the importance of understanding neonatal physiology for appropriate fluid therapy.
  • Emphasized the need for tailored fluid strategies in surgical neonates with organ dysfunction.

Conclusions:

  • Neonatal fluid management during surgery necessitates a distinct approach compared to older pediatric patients.
  • Basic physiological understanding is crucial for optimizing fluid maintenance and replacement in surgical neonates.
  • Further research and specific guidelines are needed for neonatal perioperative fluid therapy.