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Published on: February 13, 2016
Cell microcarriers and microcapsules of stimuli-responsive polymers
Amanda K Andriola Silva Brun-Graeppi1, Cyrille Richard, Michel Bessodes
1Université d'Évry Val d'Essonne, École doctorale des Génomes Aux Organismes, Boulevard François Mitterrand, F-91025 Evry cedex, France.
Summary
Stimuli-responsive polymers are advancing cell microcarriers and microcapsules for biotechnology. This review details their properties, chemistry, production, and characterization for enhanced cell applications.
Area of Science:
- Biotechnology and biomaterials science.
- Polymer chemistry and engineering.
- Cell biology and tissue engineering.
Background:
- Cell microcarriers and microcapsules offer versatile platforms for various biotechnological applications.
- Stimuli-responsive polymers enable dynamic control over microcarrier and microcapsule properties.
- Understanding these systems is crucial for developing advanced cell-based therapies and diagnostics.
Purpose of the Study:
- To provide a comprehensive overview of cell microcarriers and microcapsules in biotechnology.
- To highlight advancements achieved using stimuli-responsive polymers.
- To detail the fundamental aspects of these microsystems, including properties, chemistry, production, and characterization.
Main Methods:
- Literature review focusing on stimuli-responsive polymers for cell microcarriers and microcapsules.
- Identification and analysis of key properties and chemical mechanisms.
- Description of production methodologies and characterization techniques.
Main Results:
- Key properties of cell microcarriers and microcapsules were identified.
- The chemistry and gel formation mechanisms of relevant stimuli-responsive polymers were described.
- Production methods and characterization techniques were presented.
Conclusions:
- Stimuli-responsive polymers significantly enhance the potential of cell microcarriers and microcapsules in biotechnology.
- This review consolidates essential knowledge on the design, production, and evaluation of these advanced biomaterials.
- Further research in this area promises novel applications in regenerative medicine and beyond.
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