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Updated: Jun 7, 2026
07:36
Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting
Published on: May 1, 2015
[Lemierre's syndrome]
P Courtin1, A Toro, M Gazagnes
1Service de réanimation, centre hospitalier de Martigues, 3, boulevard des Rayettes, BP 50248, 13698 Martigues cedex, France. patrick.courtin@ch-martigues.fr
Annales Francaises D'Anesthesie Et De Reanimation
|November 2, 2010
Summary
Lemierre's syndrome, a rare but serious infection, can be effectively treated with prompt antibiotic therapy targeting anaerobes and anticoagulation. Early intervention in this case led to a favorable outcome, highlighting the importance of rapid diagnosis and management.
Area of Science:
- Infectious Diseases
- Microbiology
- Vascular Surgery
Background:
- Lemierre's syndrome is a rare condition characterized by significant morbidity and mortality, primarily affecting young adults.
- It often follows a pharyngeal infection and can progress to septic thrombophlebitis of the internal jugular vein.
Observation:
- A case presentation of Lemierre's syndrome in a young adult with typical symptoms: angina, internal jugular vein septic thrombosis, and pulmonary septic metastasis.
- Blood cultures identified Fusobacterium necrophorum as the causative agent.
Findings:
- Rapid initiation of anaerobic-targeting antibiotic therapy for 4-6 weeks was crucial for treatment.
- Anticoagulation was administered for 4 weeks, contributing to the favorable outcome.
Implications:
- This case underscores the importance of prompt diagnosis and aggressive management of Lemierre's syndrome.
- Effective treatment involves targeted antibiotics and anticoagulation to prevent severe complications and mortality.
- Early recognition of clinical features like angina and septic thrombosis is key for timely intervention.
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