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Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting

Published on: May 1, 2015

[Lemierre's syndrome].

P Courtin¹, A Toro, M Gazagnes

¹Service de réanimation, centre hospitalier de Martigues, 3, boulevard des Rayettes, BP 50248, 13698 Martigues cedex, France. patrick.courtin@ch-martigues.fr

Annales Francaises D'Anesthesie Et De Reanimation

|November 2, 2010

Summary

This summary is machine-generated.

Lemierre's syndrome, a rare but serious infection, can be effectively treated with prompt antibiotic therapy targeting anaerobes and anticoagulation. Early intervention in this case led to a favorable outcome, highlighting the importance of rapid diagnosis and management.

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Published on: September 19, 2019

Area of Science:

Infectious Diseases
Microbiology
Vascular Surgery

Background:

Lemierre's syndrome is a rare condition characterized by significant morbidity and mortality, primarily affecting young adults.
It often follows a pharyngeal infection and can progress to septic thrombophlebitis of the internal jugular vein.

Observation:

A case presentation of Lemierre's syndrome in a young adult with typical symptoms: angina, internal jugular vein septic thrombosis, and pulmonary septic metastasis.
Blood cultures identified Fusobacterium necrophorum as the causative agent.

Findings:

Rapid initiation of anaerobic-targeting antibiotic therapy for 4-6 weeks was crucial for treatment.
Anticoagulation was administered for 4 weeks, contributing to the favorable outcome.

Implications:

This case underscores the importance of prompt diagnosis and aggressive management of Lemierre's syndrome.
Effective treatment involves targeted antibiotics and anticoagulation to prevent severe complications and mortality.
Early recognition of clinical features like angina and septic thrombosis is key for timely intervention.